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Somatoform Disorders clinical trials

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NCT ID: NCT02379364 Completed - Clinical trials for Patellofemoral Pain Syndrome

Diacutaneous Fibrolysis and Patellofemoral Pain Syndrome

Start date: May 2015
Phase: Phase 3
Study type: Interventional

The aim of the study will be to assess the effectiveness of Diacutaneous Fibrolysis technique on pain, range of motion (Patellofemoral joint mobility test and muscle length test), strength and function in patients with Patellofemoral Pain Syndrome and muscle shortening. Muscle imbalance is one of most important factor associated with Patellofemoral Pain Syndrome. Shortening of lateral muscles of the thigh have a close relationship with patella position and tracking and patellofemoral pain. The scientific evidence for effectiveness of any soft tissue mobilization technique in patellofemoral pain syndrome patients is poor. Diacutaneous Fibrolysis is a non-invasive physiotherapeutic technique to release adherences and fibrosis between the different musculoskeletal structures. Diacutaneous Fibrolysis is applied by a set of metallic hooks having the advantage of allowing a deeper and more precise application, which could not be achieved manually. The present study evaluates the effectiveness of Diacutaneous Fibrolysis technique applied in the soft tissues more related with patellofemoral pain.

NCT ID: NCT02350296 Completed - Pain Disorders Clinical Trials

Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution

Start date: November 26, 2014
Phase: Phase 1
Study type: Interventional

Objectives: The objective of the study was to investigate the bioequivalence between two formulations containing ketoprofen lysine salt (KLS) when administered as single oral doses in two consecutive study periods to healthy male and female volunteers under fasting conditions. Primary end-point: to evaluate the bioequivalent rate (Cmax) and extent (AUC0-t) of absorption of ketoprofen after single dose administration of test and reference products. Secondary end-points: - to describe the pharmacokinetic (PK) profile of ketoprofen after single dose administration of test and reference products; - to collect safety and tolerability data after single dose administration of test and reference products.

NCT ID: NCT02349256 Recruiting - Clinical trials for Somatic Syndrome Disorder

Somatoform Disorder in British South Asians

Start date: December 2014
Phase: N/A
Study type: Observational

The study uses in depth interviews to understand their experience of somatoform disorder, possible explanations and their experience of somatoform disorder, possible explanations and their understanding of treatments, especially their ideas about psychosocial treatments.

NCT ID: NCT02346071 Completed - Clinical trials for Somatoform Disorders

Acceptance and Commitment Group Therapy for Adolescents With a Range of Functional Somatic Syndromes

Start date: January 30, 2015
Phase: N/A
Study type: Interventional

Background: An increasing number of adolescents report recurrent functional somatic symptoms. Some experience persistent symptoms and may receive functional somatic syndromes (FSS) diagnoses (i.e. symptoms not attributable to any known conventionally defined physical disease), characterised by severe disability and reduced quality of life. The aim of this study is to: 1. Develop an Acceptance and Commitment Therapy (ACT)-based group intervention for adolescents with severe FSS (conceptualized as Bodily Distress Syndrome (BDS), see detailed description). 2. Examine the efficacy of group based ACT in adolescents (aged 15-19 years) with severe FSS. The ACT-based treatment, with 9 sessions of group therapy and one follow up meeting is compared to standard treatment/enhanced usual care, which is one single advisory consultation. The study includes approximately 120 patients.

NCT ID: NCT02333617 Terminated - Clinical trials for Patellofemoral Pain Syndrome

Manual Therapy to Treat Gluteus Medius Trigger Points

Start date: January 2015
Phase: N/A
Study type: Interventional

This is a blinded randomized controlled trial to assess the effectiveness of manual therapy to improve hip abduction strength in patients with acute anterior knee pain. The primary objective of this study is to see if manual therapy to the gluteus medius can significantly alter within-session measurements of hip abductor strength in patients with anterior knee pain. The secondary objective of this study is to see if manual therapy to the gluteus medius can significantly alter within session pain in patients with anterior knee pain.

NCT ID: NCT02322515 Completed - Clinical trials for Anterior Knee Pain Syndrome

Patellar Taping on Proprioceptive Exercises in Young Women With Patellofemoral Pain Syndrome

Tapping
Start date: January 2015
Phase: N/A
Study type: Interventional

The relevance of this study is to determine the effects of a patellar taping on muscle activation of the vastus medialis oblique (VMO), vastus lateralis (VL) and gluteus medius (GM) during different proprioceptive exercises frequently utilized in rehabilitation program.

NCT ID: NCT02321566 Terminated - Clinical trials for Glossopharyngeal Neuralgia

Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.

Start date: February 2015
Phase: Phase 1
Study type: Interventional

This study is an open-label study to determine the feasibility of Motor Cortex Stimulation (MCS) in the treatment of patients with chronic pain of the face or upper extremity. MCS will be delivered by use of an electrode and pulse generator, which are FDA approved for spinal cord stimulation but are not approved for MCS. The study has as a single-arm design with the subject at baseline serving as a control for the response to MCS.

NCT ID: NCT02293083 Completed - Clinical trials for Myofascial Pain Syndrome

Hyaluronidase for Trigger Point Injection in Myofascial Pain Syndrome

Start date: April 2010
Phase: N/A
Study type: Interventional

Myofascial pain syndrome (MPS) is the most common cause of persistent regional pain characterized by myofascial trigger points. Trigger point injection (TPI) using local anesthetics is one of the most effective methods for treatment of MPS, and steroids or botulinum toxin can be added to local injections . Recent study suggested that the hyaluronan (HA) could be the basis of myofascial pain. HA within the deep fascia facilitates the free sliding of two adjacent fibrous fascial layers. If the HA assumes a more packed conformation, or more generally, if the loose connective tissue inside the fascia alters its density, the behavior of the entire deep fascia and the underlying muscle would be compromised. The investigators anticipated that hyaluronidase could decrease the viscosity of HA near the muscle and fascia of trigger points. Meanwhile, hyaluronidase is thought to promote the spread of local anesthetic solution by hydrolyzing glycosidic bonds within HA. Hyaluronidase was shown to be effective in retro- and peribulbar block for ophthalmologic surgery or reducing tissue edema in dermatology, and adhesiolysis for some interventional pain managements. However, the effect of the addition of hyaluronidase to local anesthetics during TPI has not been studied. The investigators aimed to compare the efficacy of TPI with the addition of hyaluronidase compared to local anesthetic alone on pain and quality of life in MPS patients.

NCT ID: NCT02250144 Recruiting - Clinical trials for Patellofemoral Pain Syndrome

Foot Orthoses in Patellofemoral Pain Syndrome: a Prospective Randomized Study of Morpho-specific Versus Placebo Orthoses

Start date: June 2015
Phase: N/A
Study type: Interventional

Patellofemoral pain syndrome is one of the most common musculoskeletal disorders. It is defined as an anterior knee pain. Its origin is a conflict during patellar tracking, due to patellofemoral malalignment and soft tissue overload. A few recent studies seem to show a benefit of prefabricated feet orthoses in patellofemoral pain syndrome, alone or in association with rehabilitation. However, no one has analyzed the outcome of morpho-specific foot orthoses in a prospective randomized study. The purpose of this prospective randomized study is to compare clinical outcomes in daily living and in sports activities, between morpho-specific and placebo foot orthoses. Morpho-specific foot orthoses are designed according to the patient's morphotype. They are intended to correct structural defects of the hindfoot, midfoot and forefoot, in the aim to correct abnormal overload during patellofemoral tracking.

NCT ID: NCT02243332 Completed - Clinical trials for Patellofemoral Pain Syndrome

Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this small, pilot study is to evaluate a novel device that uses neuromuscular electrical stimulation to assist quadriceps muscles as a user walks. This study will involve use of this device on individuals with patellofemoral pain, a relatively common injury among active people, to see if quadriceps stimulation could mitigate disparities in quadriceps activation timing that may indirectly lead to knee pain.