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Clinical Trial Summary

This is a first-in-human, open-label, uncontrolled, multi-center, monotherapy dose-escalation and dose expansion study of RO7444973.The aim of this study is to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of RO7444973 in participants with unresectable and/or metastatic melanoma-associated antigen A4 (MAGE-A4)-positive, solid tumors, carrying the HLA-A*02:01 allele.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05129280
Study type Interventional
Source Hoffmann-La Roche
Contact
Status Terminated
Phase Phase 1
Start date January 25, 2022
Completion date July 12, 2023

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