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A Study of PRS-344/S095012 (PD-L1x4-1BB Bispecific Antibody-Anticalin Fusion) in Patients With Solid Tumors

Solid Tumor Clinical Trial

Official title:
A First in Human Phase 1-2 Open-Label, Multicenter, Dose Escalation and Expansion Study of PRS-344/S095012 in Patients With Solid Tumors

Clinical Trial Summary

This is a first-in-human (FIH), phase 1/2, multi center, open-label, dose escalation and cohort expansion study designed to determine the safety and tolerability of PRS-344/S095012 in patients with advanced and/or metastatic solid tumors.

Clinical Trial Description

The trial is an open-label, multi-center safety trial of PRS-344/S095012. The trial consists of two parts, a dose escalation part (phase 1, first-in-human (FIH) and an expansion part (phase 2)). The expansion part of the trial will be initiated once the optimal biological dose (OBD) has been determined. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05159388
Study type Interventional
Source Servier
Contact Kayti Aviano
Phone 781-605-8632
Email aviano@pieris.com
Status Recruiting
Phase Phase 1/Phase 2
Start date September 8, 2021
Completion date October 31, 2027
View Details
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