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A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors

Solid Tumor Clinical Trial

Official title:
A Phase 1, First In Human Study of DS-1055a in Subjects With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors

Clinical Trial Summary

The purpose of this study is to assess the safety and tolerability of DS-1055a in participants with relapsed or refractory locally advanced or metastatic solid tumors for which no standard treatment is available.

Clinical Trial Description

This Phase 1, open-label, non-randomized, dose escalation, first-in-human study will assess the safety and tolerability of DS-1055a, determine the maximum tolerated dose of DS-1055a, pharmacokinetic (PK) properties of DS-1055a, and the incidence of anti-drug antibodies (ADAs) against DS-1055a and other antibodies. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04419532
Study type Interventional
Source Daiichi Sankyo
Contact (Asia sites) Daiichi Sankyo Contact for Clinical Trial Informati
Phone +81-3-6225-1111(M-F 9-5 JST)
Email dsclinicaltrial@daiichisankyo.co.jp
Status Recruiting
Phase Phase 1
Start date October 9, 2020
Completion date December 31, 2024
View Details
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