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Solid Tumor, Adult clinical trials

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NCT ID: NCT05620472 Enrolling by invitation - Solid Tumor, Adult Clinical Trials

Molecular Imaging of EpCAM Receptors Using [99mTc]Tc(CO)3-(HE)3-Ec1

Start date: October 1, 2022
Phase: Phase 1
Study type: Interventional

The study should evaluate the biological distribution of [99mTc]Tc(CO)3-(HE)3-Ec1 in patients with solid tumor The primary objective are: 1. To assess the distribution of [99mTc]Tc(CO)3-(HE)3-Ec1 in normal tissues and tumors at different time intervals. 2. To evaluate dosimetry of [99mTc]Tc(CO)3-(HE)3-Ec1 . 3. To study the safety and tolerability of the drug [99mTc]Tc(CO)3-(HE)3-Ec1 after a single injection in a diagnostic dosage. The secondary objective are: 1. To compare the obtained [99mTc]Tc(CO)3-(HE)3-Ec1 SPECT imaging results with the data of CT and/or MRI and/or ultrasound examination and immunohistochemical (IHC) studies in solid tumor patients.

NCT ID: NCT03929653 Enrolling by invitation - Solid Tumor, Adult Clinical Trials

Personalized Therapy of Molecular Tumor Board Participation With the Guidance of Next Generation Sequencing

Start date: June 1, 2017
Phase:
Study type: Observational

This study seeks to evaluate the clinical value of the personalized therapy model with the guidance of Molecular Tumor Board (MTB) after Next Generation Sequencing(NGS), and to track patient outcomes.

NCT ID: NCT03927599 Enrolling by invitation - Solid Tumor, Adult Clinical Trials

Advanced Refractory Solid Tumors With TP53 Mutations Register Study

Start date: August 1, 2018
Phase:
Study type: Observational

The efficacy and safety of the PARP inhibitor in combination with the VEGFR inhibitor will be investigated in advanced refractory solid tumors patients with TP53 mutation .

NCT ID: NCT03326479 Enrolling by invitation - Solid Tumor, Adult Clinical Trials

POA Retrospective Repository

Start date: November 30, 2016
Phase: N/A
Study type: Observational

This repository is a multi-center, outcomes study designed to retrospectively collect data on the demographics, presentation, diagnosis, treatment, cost of associated care, quality of life, and outcomes of subjects utilizing Caris Molecular Intelligence® (CMI) Services for the treatment of cancer. Prior to enrolling a subject, the subject's physician will have made the independent decision whether or not to utilize the drug associations provided by CMI and made clinical treatment choices as appropriate. Thus, data captured and reported provides a "real world" perspective on diagnosis, treatment, cost, and outcomes.

NCT ID: NCT03324841 Enrolling by invitation - Solid Tumor, Adult Clinical Trials

POA Prospective Repository

Start date: June 7, 2017
Phase:
Study type: Observational [Patient Registry]

This repository is a multi-center, outcomes study designed to collect data on the demographics, presentation, diagnosis, treatment, cost of associated care, quality of life, and outcomes of subjects utilizing Caris Molecular Intelligence® (CMI) Services for the treatment of cancer.