Clinical Trials Logo

Clinical Trial Summary

The study consists of two stages. In Stage 1, maximum tolerated dose (MTD) will be determined. In Stage 2, additional patients will be treated at the MTD of GDC-0152.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT00977067
Study type Interventional
Source Genentech, Inc.
Contact
Status Terminated
Phase Phase 1
Start date June 2007
Completion date November 2009

See also
  Status Clinical Trial Phase
Completed NCT01301716 - A Study of the Safety and Pharmacology of GDC-0980 in Combination With Either Paclitaxel and Carboplatin (With or Without Bevacizumab) or Pemetrexed and Cisplatin in Patients With Solid Tumors Phase 1
Completed NCT00968981 - A Study of Hedgehog Pathway Inhibitor GDC-0449 in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists Phase 1
Completed NCT00747734 - A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors Phase 1
Completed NCT01226277 - A Study Evaluating the Safety, Tolerability and Pharmacokinetics of GDC-0917 Administered to Patients With Refractory Solid Tumors or Lymphoma Phase 1
Completed NCT00876109 - A Study of GDC-0941 in Participants With Locally Advanced or Metastatic Solid Tumors for Which Standard Therapy Either Does Not Exist or Has Proven Ineffective or Intolerable Phase 1
Completed NCT01209143 - A Study of Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists Phase 1
Completed NCT00996892 - A Study Evaluating the Safety, Tolerability and Pharmacokinetics of GDC-0973 in Combination With GDC-0941 When Administered in Patients With Locally Advanced or Metastatic Solid Tumors Phase 1
Recruiting NCT03514368 - Monitoring of Immunological Mechanisms and Biomarkers Underlying Efficacy and Toxicity of Cancer Immunotherapy N/A
Completed NCT00909740 - A Study of the Safety and Pharmacokinetics of MEGF0444A Administered to Patients With Advanced Solid Tumors Phase 1
Completed NCT00096941 - A Study to Evaluate Subjects Treated With rhuMab 2C4 (Pertuzumab) in a Previous Genentech Phase II Cancer Study Phase 2
Completed NCT01820299 - Phase I Assay-guided Trial of Anti-inflammatory Phytochemicals in Patients With Advanced Cancer Phase 1
Completed NCT01546519 - A Study of the Hedgehog Pathway Inhibitor Vismodegib in Patients With Advanced Solid Malignancies Including Hepatocellular Carcinoma With Varying Degrees of Renal or Hepatic Function Phase 1
Completed NCT01090960 - A Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors Phase 1
Completed NCT01296555 - A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer Phase 1
Completed NCT01139723 - A Study of the Safety and Pharmacokinetics of MINT1526A, Administered Intravenously As a Single Agent and in Combination With Bevacizumab to Patients With Advanced Solid Tumors Phase 1
Completed NCT01332604 - GDC-0980 in Combination With a Fluoropyrimidine, Oxaliplatin, and Bevacizumab in Patients With Advanced Solid Tumors Phase 1
Completed NCT00927589 - A Study to Evaluate Corrected QT Interval and Drug-Drug Interaction of Trastuzumab on Carboplatin in the Presence of Docetaxel in Patients With HER2-Positive Metastatic or Locally Advanced Inoperable Cancer Phase 1
Recruiting NCT05228106 - 68Ga-PSMA-617 PET/CT for PSMA-expressing Tumor: a Pragmatic Study
Completed NCT02323191 - A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors Phase 1
Completed NCT01075464 - A Study of the Safety and Pharmacology of MEGF0444A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advanced or Metastatic Solid Tumors Phase 1