Solar Skin Damage Clinical Trial
— CHOCOPOOfficial title:
Flavanols and Skin Photo Protection: a Double Blind Clinical Trial
Verified date | May 2012 |
Source | Laval University |
Contact | n/a |
Is FDA regulated | No |
Health authority | Canada: Health Canada |
Study type | Interventional |
As flavanols have antioxidants, anti-inflammatory and anti-DNA damaging effects and may increase microcirculation in skin, the purpose of the study is to investigate the chronic effect of flavanol-rich chocolate as an effective strategy to protect against the harmful effect of ultraviolet (UV) radiation.
Status | Completed |
Enrollment | 78 |
Est. completion date | May 2013 |
Est. primary completion date | September 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 20 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Non-smoking women between the ages of 20 and 65 years. - Normal skin of type I and II as decried by Fitzpatrick classification. Exclusion Criteria: - Pregnancy and breast feeding. - Photo sensibility: history of skin cancers, photosensitizing medication. - Sun bed use or sunbathing in the previous 3 months. - Use of supplements or natural health products (fish oils, coenzyme Q10, garlic, lycopene, beta carotene). - Allergy or intolerance to nuts or chocolate. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Canada | Laval university, Department of Medicine, Institut des nutraceutiques et des aliments fonctionnels. | Québec | Quebec |
Lead Sponsor | Collaborator |
---|---|
Laval University |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in Minimal erythema dose | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption | No | |
Secondary | Change in Skin elasticity | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption | No | |
Secondary | Change in Skin moisture | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption | No | |
Secondary | Change in levels of Vitamin D and polyphenols | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
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