Impact of Coffeeberry Extract on Skill Performance During Simulated Match Play in Academy Football Players

Soccer Performance Clinical Trial

Official title:

Impact of Coffeeberry Extract on Skill Performance During Simulated Match Play in Academy Football Players

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05547204
• Other study ID #: PEP-2114
• Status: Completed
• Phase: N/A
• Start date: June 30, 2022
• Est. completion date: December 4, 2022

Study information

• Verified date: March 2023
• Source: PepsiCo Global R&D
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study of soccer skill performance has three objectives:

1. Compare effects of coffeeberry (300mg) and placebo ingestion on dribbling speed and precision, passing speed and accuracy, and sprint speed during a full simulated soccer match.

2. Compare effects of coffeeberry (300mg) and placebo ingestion on subjective measures (mental / physical energy and activation-deactivation (feelings or mood) during a full simulated soccer match.

3. Compare effects of coffeeberry (300mg) and placebo ingestion on chlorogenic acid (CGA) and caffeine metabolites in the blood 1-hour post ingestion, and other blood metabolites (glucose/lactate) throughout the simulated soccer match.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Est. completion date: December 4, 2022
• Est. primary completion date: December 4, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 16 Years to 28 Years

Eligibility

Inclusion Criteria:

• Provide valid informed consent prior to any study procedure

• Male soccer players age 16 to 28 years.

• >= 5-year soccer playing experience

• >= 1-year regularly soccer training

• Free of injuries

• Willing to avoid alcohol in the 48-h period prior to all visits

• Willing to avoid caffeinated products and apples, berries/cherries for 24-h prior to all visits

• Willing to record food intake over the 48-h period prior to the first trial and replicate for second trial

• Willing to abstain from strenuous physical activity for 24-h before all visits

Exclusion Criteria:

• Smoking

• Cardiovascular diseases

• Diabetes or other metabolic disease • Hypertension (>140/>90 mm Hg)

• Presence of injuries

• Major illnesses or surgery in prior 90 days

• Participation in another clinical trial in the past month

Related Conditions & MeSH terms

• Coffeeberry Effects
• Skill Performance
• Soccer Performance

Intervention

Other:
• Beverage
Free from added carbohydrates (contain 1g CHO only) and electrolytes are absent.

Locations

Country	Name	City	State
United Kingdom	U. Stirling, Health Science and Sport	Stirling	Scotland

Sponsors (1)

Lead Sponsor	Collaborator
PepsiCo Global R&D

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Dribbling speed	m/sec, increase would be better. Simulated soccer match in an indoor gym with pre-set targets.	Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
Primary	Dribbling precision	Meters, more accuracy would be better. Simulated soccer match in an indoor gym with pre-set targets.	Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
Primary	Passing accuracy	1 to 10 scale, a higher score would be better. Simulated soccer match in an indoor gym with pre-set targets.	Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match.
Primary	Passing speed	km/h, increased passing speed would be better. Simulated soccer match in an indoor gym with pre-set targets.	Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
Primary	Sprint speed.	m/sec, increased sprint speed would be better. In indoor gym with marked course.	Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
Secondary	Blood analyte: Chlorogenic acid (CGA)	mmol/L to evaluate primary outcomes. n.a. for placebo. Capillary blood draw for frozen plasma analysis	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Blood analyte: Caffeine metabolites	ug/ml, to evaluate primary outcomes. n.a. for placebo. Capillary blood draw for frozen plasma analysis	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Blood analyte: Glucose	mmol/L, more regulated would be better. Capillary blood draw for frozen plasma analysis	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Blood analyte: Lactate	mmol/L, lower (delayed rise) would be better. Capillary blood draw for frozen plasma analysis	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Rating of perceived exertion (RPE)	By Borg scale, rated 6 to 20, very very light to very very hard. Lower values would be better	Half-time and end of match (3.5 hours)
Secondary	Activation-deactivation (feelings or mood)	Checklist of 20 feelings using a 4 point scale from definitely do feel to definitely don't feel. More relaxed feelings or in a better mood would be better.	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Mental energy	Visual Analog Scale (VAS), vertical marking on 100 mm horizontal line. Higher energy would be better	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Physical energy	Visual Analog Scale (VAS), vertical marking on 100 mm horizontal line. Higher energy would be better	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Gut comfort	Visual Analog Scale (VAS), vertical marking on 100 mm horizontal line. No or less nausea, fullness or bloating would be better	Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
Secondary	Heart rate	By electronic reading. Lower would be better.	Continuous from pre-dose baseline through end of match (3.5 hours)
Secondary	Hydration status	Urine osmolality in mOsm/kg change in concentration pre- vs. post-exercise	Pre-dose baseline and end of match (3.5 hours)