Clinical Trials Logo
  1. Home
  2. Snoring
  3. NCT05382494

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children — MIST+  

Snoring Clinical Trial

Official title:
Efficacy of Intranasal Steroid for Children With Sleep-Disordered Breathing Non-Responsive to Initial Treatment With Intranasal Saline: A Randomized Trial

Clinical Trial Summary

MIST+ is studying a nasal spray to see if it will reduce the need for surgery for snoring. Children aged 3-12 are invited to take part. Snoring affects up to 10% of children and can cause sleeping problems and concentration or behavioural issues in the daytime. Currently the most common treatment for snoring is surgery to remove the tonsils and/or adenoids, however many children wait a long time to see a specialist. This research is trying to find if nasal sprays can help children with snoring, and whether this can reduce the need for surgery.

Clinical Trial Description

MIST+ is a multi centre, double-blind, placebo controlled trial. Children 3-12 years of age, who do not respond to a run-in phase of 6 weeks of normal saline intranasal spray to treat sleep disordered breathing, will be randomised 1:1 to a treatment phase of either intranasal corticosteroid (investigational product) or normal saline (placebo). Participants will receive treatment for 6 weeks and receive follow up at at 12 weeks, 6, and 12 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05382494
Study type Interventional
Source Murdoch Childrens Research Institute
Contact
Status Active, not recruiting
Phase Phase 4
Start date December 5, 2022
Completion date December 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05371509 - Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study N/A
Active, not recruiting NCT02470182 - Screening for Sleep Disordered Breathing With Minimally Obtrusive Sensors
Completed NCT03964324 - NO Measurements in Screening for Asthma and OSA, in Patients With Severe Snoring N/A
Completed NCT06186687 - Rehabilitative Approaches: Myofunctional Therapy and Retropalatal Narrowing and Snoring N/A
Completed NCT03640793 - Prospective Evaluation of a Palato-Pharyngeal Implant System (PPIS) Obstructive Sleep Apnea Syndrome (OSAS) N/A
Completed NCT03333876 - In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study N/A
Not yet recruiting NCT04143022 - Evaluation of the Effects of Acupuncture Press Needle in Mild to Moderate Obstructive Sleep Apnea Patients N/A
Completed NCT02834767 - Genioglossus Muscle Training for Snoring and Obstructive Sleep Apnea N/A
Terminated NCT01772017 - A Trial to Evaluate a Device for the Treatment of OSA and Snoring N/A
Withdrawn NCT01680380 - Tracking Breathing During Sleep With Non-contact Sensors N/A
Unknown status NCT00806637 - Vessel Sealing System Uvulopalatoplasty Versus Uvulopalatal Flap N/A
Completed NCT00560859 - Childhood Adenotonsillectomy Study for Children With OSAS N/A
Terminated NCT03701165 - The Effect of the DryMouth Shield on Snoring N/A
Active, not recruiting NCT05643352 - Barbed Reposition Pharyngoplasty in Patients Complaining of Unilevel Palatal Snoring N/A
Recruiting NCT05756647 - Mandibular Advancement vs Home Treatment for Primary Snoring Phase 2
Completed NCT04086407 - Apnea Hypopnea Index Severity Versus Head Position During Sleep N/A
Not yet recruiting NCT05116657 - Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome
Completed NCT01491828 - Study to Determine Results of Vibratory Stimulus on Subject's Neck Phase 1
Completed NCT01322334 - Singing Exercises to Improve Symptoms of Snoring and Sleep Apnea N/A
Terminated NCT03316963 - Neostigmine For Snoring During DISE Early Phase 1