Cryotherapy as a Coadjuvant in Crotaline Snakebite Management With Antivenom.

Snake Bites Clinical Trial

Official title: Cryotherapy as a Coadjuvant in the Management of Crotaline Snakebite With F(ab')2 Antivenom: A Randomized Pilot Study.

Status Completed

Clinical Trial Summary

The study aimed to determine the effect of local cryotherapy as a coadjuvant in patients with snakebite treated with F(ab')2 therapy venom at the Hospital Juárez de Mexico.

Clinical Trial Description

Introduction: Local cryotherapy induces vasoconstriction, which leads to a reduction in the inflammatory process. However, the efficacy of local cryotherapy as a coadjuvant in snakebite treatment with F(ab')2 antivenom is unknown.

Objective: Determine the effect of local cryotherapy as a coadjuvant in patients with snakebite treated with F(ab')2 therapy venom.

Material and methods: Subjects with snakebite envenomation accident grade II, according to the Christopher-Rodning classification, were enrolled from the Clinical Toxicology Service of the Hospital Juárez de México. One group of patients received F(ab')2 antivenom therapy (antivipmyn®) plus local cryotherapy, and another group received only F(ab')2 antivenom therapy. ;

Related Conditions & MeSH terms

• Snake Bites

• NCT number: NCT04470791
• Study type: Interventional
• Source: Hospital Juarez de Mexico
• Status: Completed
• Phase: N/A
• Start date: January 1, 2015
• Completion date: July 1, 2017