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Clinical Trial Summary

PREVENT is a multicentre, 2x2 factorial, randomized clinical trial that aims to determine the effect of cytisine versus placebo, as well as the effect of video messaging to support smoking cessation versus standard of care in perioperative patients. This trial aims to investigate the effects of cytisine and text messaging on 6-month continuous abstinence rates. PREVENT will also assess secondary outcomes at 30 days, 56 days and 6 months post-randomization: 7-day point prevalence abstinence, urge to smoke, time to first lapse, time to relapse, number of cigarettes smoking if still smoking, pulmonary complications, vascular complications, wound and infectious complications, stroke, time in hospital and acute hospital care.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05102123
Study type Interventional
Source Population Health Research Institute
Contact Emily Di Sante
Phone 905-297-3479
Email emily.disante@phri.ca
Status Recruiting
Phase Phase 3
Start date January 15, 2024
Completion date January 1, 2027

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