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Cytisine Versus Varenicline for Smoking Cessation — RAUORA  

Smoking Cessation Clinical Trial

Official title:
RAUORA: Cytisine Versus Varenicline for Smoking Cessation

Clinical Trial Summary

To evaluate the effectiveness, safety, and cost-effectiveness of cytisine plus behavioural support compared to varenicline plus behavioural support for smoking cessation, in indigenous Māori (or family of Māori) who smoke and are motivated to quit.

Clinical Trial Description

Cytisine, a natural product, found in plants such as the Golden Rain and New Zealand Kowhai, partially blocks the effects of nicotine on the brain. Cytisine has been used as a smoking cessation treatment in several Central and Eastern European countries since the 1960s, is inexpensive compared to other cessation medications and has few known side effects. New Zealand research has shown cytisine to be more effective than nicotine replacement therapy at helping people quit smoking. Using a clinical trial design (N=2140) the investigators plan to investigate whether cytisine is at least as good as varenicline (the most effective, but most expensive, smoking cessation medication currently available in New Zealand) for helping Māori/family of Māori who smoke, to quit. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02957786
Study type Interventional
Source University of Auckland, New Zealand
Contact
Status Completed
Phase Phase 3
Start date September 18, 2017
Completion date October 10, 2019
View Details
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