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Smoking Cessation clinical trials

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NCT ID: NCT02046408 Completed - Smoking Cessation Clinical Trials

Computer-Facilitated 5A's for Smoking Cessation in Primary Care

Start date: July 2012
Phase: N/A
Study type: Interventional

This study tests the use of handheld computer tablets to promote the integration of 5A's (Ask, Advise, Assess, Assist, Arrange) for smoking cessation in academic and community primary care clinics. Although most patients receive the "ask" and "advise" steps, only slightly more than half are "assessed" for readiness to change, less than half receive "assistance" in changing, and only 9% have an "arranged" follow-up. While the large majority of primary care providers support the 5A's model, negative attitudes and the lack of time, knowledge, and cessation skills are common obstacles. Alternate service delivery systems that address these obstacles and evidence-based strategies to promote their implementation are needed to improve provider adherence and 5A's fidelity.

NCT ID: NCT02044874 Completed - Smoking Cessation Clinical Trials

A Study to Evaluate the Effect of Lorcaserin Hydrochloride on Smoking Cessation

Start date: March 2014
Phase: Phase 2
Study type: Interventional

In smokers who are motivated to stop smoking, treatment with lorcaserin compared with placebo will provide greater abstinence as measured by the last 4 weeks of treatment (Weeks 9-12). The target quit date was Day 15.

NCT ID: NCT02037360 Completed - Smoking Cessation Clinical Trials

Mobile Mindfulness Training for Smoking Cessation

Start date: August 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectiveness of a Mobile Mindfulness Training smartphone application on smoking cessation in smokers ages 18 to 65 years.

NCT ID: NCT02020005 Completed - Smoking Cessation Clinical Trials

Evaluation of Cessation Preferences of Menthol Smokers

Start date: September 2013
Phase: N/A
Study type: Interventional

The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, mint-flavored nicotine gum; non-flavored nicotine gum; mentholated nicotine inhaler; and non-menthol nicotine inhaler. Participants will undergo an orientation and baseline assessment followed by a 2-week product sampling phase. At the end of the 2 weeks of sampling, subjects will select a product to use during the following 2-week smoking cessation phase. This 2-week abstinence phase is followed by one week of abrupt withdrawal of the product. This study design was successfully used in a study we conducted that examined the smokers' preference for a variety or oral tobacco products.

NCT ID: NCT02010697 Completed - Smoking Cessation Clinical Trials

Nonsmokers Helping Smokers Quit

Project BEST
Start date: December 2013
Phase: N/A
Study type: Interventional

This study examines whether nonsmokers can be mobilized to help smokers quit. We will test, via mail campaign, whether targeting nonsmokers can be equally effective in increasing smokers' quit rate as targeting smokers directly. The hypothesis is that both targeted interventions will lead to a higher quit rate than a control group, which receives one set of self-help materials. Each of the targeted intervention groups receives 10 mailings. Smoking status of all three groups will be measured at 3 and 7 months post randomization.

NCT ID: NCT01997151 Completed - Smoking Cessation Clinical Trials

Promoting Health During Pregnancy: A Multiple Behavior Computer Tailored Intervention

Start date: December 2011
Phase: N/A
Study type: Interventional

This program of research tested the effectiveness of an iPad delivered multiple behavior intervention grounded in the Transtheoretical Model of Behavior Change for pregnant women. It was hypothesized that the intervention would reduce the number of health behavior risks reported by pregnant women in the treatment group. The target behaviors of the intervention are smoking cessation and relapse prevention, stress management, and fruit and vegetable consumption.

NCT ID: NCT01978197 Completed - Smoking Cessation Clinical Trials

Evaluation of Cessation Preferences of Menthol Smokers

Start date: February 2013
Phase: Phase 4
Study type: Interventional

The primary aim of this study is to determine menthol smokers' perception, product preference, and pattern of use across six products including, 1) mint-flavored 2mg nicotine gum ; 2) mint-flavored 4mg nicotine gum; 3) non-flavored 2mg nicotine gum; 4) non-flavored 4mg nicotine gum; 5) mint-flavored electronic cigarette; and 6) non-flavored electronic cigarette. Fifty smokers (all African American menthol smokers) will be recruited for this study. Participants will undergo a baseline assessment followed by a 2-week product sampling phase.

NCT ID: NCT01974063 Terminated - Smoking Cessation Clinical Trials

Alternate Nicotine Delivery Systems and Airway Epithelial Biology

Start date: March 2013
Phase:
Study type: Observational

Cigarette smoking evokes major changes in the biology of the airway epithelium, the cell population that takes the brunt of the stress of cigarette smoke and the cell population central to the pathogenesis of chronic obstructive pulmonary disease (COPD) and lung cancer. The focus of this study is to identify the differences that two popular alternative nicotine delivery strategies, shisha and electronic cigarettes, have on the airway epithelium compared to cigarette smoking. We hypothesize that both alternative nicotine delivery strategies disorder airway epithelial biology, but in different ways than does cigarette smoking.

NCT ID: NCT01964898 Completed - Smoking Cessation Clinical Trials

Post Acute Coronary Event Smoking Study

PACES
Start date: October 2013
Phase: N/A
Study type: Interventional

Smoking and depressed mood are both predictive of mortality following Acute Coronary Syndrome. However, to date, no counseling treatment has been designed to target smoking cessation and manage mood in this population. This trial will test such a treatment based on Behavioral Activation, an approach that has shown promise as an integrated treatment for smoking and mood management in other populations.

NCT ID: NCT01947725 Recruiting - Smoking Cessation Clinical Trials

Behavioral Activation for Smoking Cessation in Veterans With PTSD

Start date: January 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to examine whether behavioral activation as an adjuvant to standard smoking cessation treatment improves smoking cessation outcomes among veterans with PTSD relative to a comparably intense combination of standard smoking cessation treatment + health and smoking education. It is expected that behavioral activation will produce more successful results than health and smoking education when paired with standard smoking cessation treatment.