Small Cell Lung Cancer Clinical Trial
Official title:
Combination of CM082 With JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC) Who Progressed on First-line Treatment: a Phase II Study
This study was a single-arm, multi-center, phase II study, which is aimed to evaluate the efficacy and safety of CM082 combined with JS001 as the second-line treatment of advanced small cell lung cancer. Eligible patients will receive CM082 tablets 150mg once daily orally in combination with JS001 (240mg, intravenously) every 21 days. Treatment continues until disease progresses , intolerable toxicity, or withdraw.
This study was a single-arm, multi-center, phase II study, which is aimed to evaluate the
efficacy and safety of CM082 combined with JS001 as the second-line treatment of advanced
small cell lung cancer. Eligible patients will receive CM082 tablets 150mg once daily orally
in combination with JS001 (240mg, intravenously) every 21 days. Treatment continues until
disease progresses , intolerable toxicity, or withdraw.
The primary endpoint is tumor response per investigator assessment according to response
evaluation criteria in solid tumors (recist) version 1.1, secondary endpoints include disease
control rate, progression-free survival, overall survival, safety and tolerability. iRECIST
is also implemented for tumor response assessment.
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