Small Bowel Obstruction Clinical Trial
— PREDIFAILOfficial title:
Assessment of a Predictive Radiologic Score to Predict the Failure of the Non-operative Management of Adhesive Small Bowel Obstruction: a Prospective Cohort Analysis
Verified date | August 2022 |
Source | University Hospital, Angers |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The management of acute adhesive small bowel obstruction remains challenging for the digestive surgeon. The Bologna guidelines recommend that conservative management of aSBO. The literature reports that this form of management has a failure rate between 10 and 40%. A radiological score has been proposed and was associated with an increased risk of failure of conservative management. This tool is promising to select patients further requiring surgery but it has to be assessed in a multi centric prospective cohort.
Status | Completed |
Enrollment | 279 |
Est. completion date | January 15, 2022 |
Est. primary completion date | December 15, 2021 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - all the consecutive patients admitted for initial non-surgical management for aSBO - during the period of inclusion Exclusion Criteria: - the cause of SBO was functional or other than adhesive - patients requiring initial surgical management. - absence of computed tomography performed at admission |
Country | Name | City | State |
---|---|---|---|
France | university hospital of Angers | Angers |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Angers |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Angers CT score | The Angers CT score =5 was considered to be risk factor for failure of the medical management.
Angers CT score was calculated by reading the CT scan as follow: beak sign (+2), if not (0) closed loop (+4), if not (0) focal (+4) or diffuse (+4) intraperitoneal liquid, if not (0) focal (+2) or diffuse (0) mesenteric haziness, if not (0) focal (-3) or diffuse (-3) mesenteric liquid, if not (0) diameter of the most dilated small bowel loop > 40 mm (-2) (if not (0). |
immediately after the completion of the CT-scan |
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