The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms

Sleep Clinical Trial

Official title:

The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03636360
• Other study ID #: Sunlike
• Status: Completed
• Phase: N/A
• Start date: July 1, 2019
• Est. completion date: March 1, 2021

Study information

• Verified date: March 2021
• Source: VA Palo Alto Health Care System
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to examine, in healthy controls, whether LED lighting that has a color spectrum similar to that of sunlight is able to differentially impact mood, circadian rhythms, sleep, and behavior, as compared to standard fluorescent lighting.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: March 1, 2021
• Est. primary completion date: March 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Good self-reported health

• Normal color vision

Exclusion Criteria:

• No sleep disorders

• No extreme chronotype

• Regular smoker

• Significant hearing loss

• Depression

• Alcohol use disorder

• Use of illegal drugs

• Pregnant

Related Conditions & MeSH terms

• Chronobiology Disorders
• Circadian Dysregulation
• Mood
• Sleep

Intervention

Device:
• Light
15 hours of light exposure

Locations

Country	Name	City	State
United States	VA Palo Alto Health Care System	Palo Alto	California

Sponsors (2)

Lead Sponsor	Collaborator
VA Palo Alto Health Care System	Seoul Semiconductor

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Alertness	Change in median reaction time score on the auditory psychomotor vigilance test	15 hours
Primary	Melatonin suppression	Amount of reduction in the concentration of salivary melatonin concentrations during an experimental light stimulus	3 hours
Secondary	Mood	Change in total positive and negative affect scores on the Positive and Negative Affect Schedule (PANAS)	15 hours