The Effects of Sleep Variability in Youth

Sleep Variability Clinical Trial

Official title:

The Effects of Sleep Variability on Sleep Quality, Daytime Functioning and Cardiometabolic Regulation in Youth

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04263428
• Other study ID #: EA1708030
• Status: Completed
• Phase: N/A
• Start date: June 1, 2019
• Est. completion date: January 1, 2021

Study information

• Verified date: May 2021
• Source: The University of Hong Kong
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Daily sleep variability is prevalent in the young populations, yet its effects remain less clear. The experimental study aims to examine the impacts of intraindividual daily sleep variability on sleep characteristics, cardiometabolic regulations and daytime functioning in college students.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 41
• Est. completion date: January 1, 2021
• Est. primary completion date: January 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• Habitual sleep duration > 7 h/day.

Exclusion Criteria:

• Extreme morning- nor extreme evening-chronotype

• With sleep problems

• With mood and anxiety problems

• With excessive daytime sleepiness

• Have history of any chronic medical condition and on regular medication.

Related Conditions & MeSH terms

• Sleep Variability

Intervention

Behavioral:
• Irregular sleep
Experimental-induced sleep variability

Locations

Country	Name	City	State
Hong Kong	Sleep Research Clinic & Laboratory, Department of Psychology, The University of Hong Kong	Hong Kong

Sponsors (1)

Lead Sponsor	Collaborator
The University of Hong Kong

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Subjective sleepiness	As measured by the Stanford Sleepiness Scalen (SSS)	7 days (every morning and evening)
Primary	Mood	mood state as measured by the Positive and Negative Affect Scale (PANAS).	7 days (every morning and evening)
Primary	Cognitive functioning - Sustained attention	Sustained attention as measured by psychomotor vigilance task (PVT)	7 days (every morning and evening)
Primary	Cognitive functioning - processing speed	Processing speed as measured by Digit Symbol Substitution Test (DSST)	7 days
Primary	Cognitive functioning - inhibition	Inhibition as measured by stop-signal reaction time (SSRT)	7 days
Primary	Cognitive functioning - working memory	working memory as measured by 2-back task	7 days
Secondary	Sleep quality	Actual sleep time, sleep onset latency, wake after sleep onset and night time arousals as measured by actigraphy and PSG. Sleep satisfactory and dreams as measured by sleep diary.	7 days
Secondary	Sleep architecture	Sleep stagings (e.g., SWS%, REM duration) and sleep EEG spectrums as analysed from PSG recordings.	7 days
Secondary	Heart rate variability	Resting heart rate and heart rate variability are measured in the morning, evening and during the night.	7 days
Secondary	Cortisol awakening response	Cortisol awakening response is assessed before and after the manipulation.	baseline, post-intervention