The Effect of Esketamine on Sleep Disturbance

Status Not yet recruiting

Clinical Trial Summary

To explore the efficacy of a single low dose of esketamine during surgical abortion in patients with sleep disturbance

Clinical Trial Description

Sleep disturbance occur in the form of sleep deprivation, circadian rhythm disturbance, and structural abnormalities. Women who requires surgical abortion due to fetal anomaly or unwanted pregnancy often experience sleep disturbance. Severe sleep disturbance is a strong indicator for postoperative sleep disorders, which can lead to postoperative delirium and cognitive dysfunction, aggravate postoperative pain, and delay postoperative recovery. Esketamine is an N-methyl-D-aspartate(NMDA) receptor antagonist with analgesic and sedative effects, and is widely used in clinical treatment of refractory depression. For patients undergoing surgical abortion, in addition to sedation and analgesia, whether the intraoperative use of esketamine has positive effects on sleep disturbance is worth exploring. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06388824
Study type	Interventional
Source	Tianjin Medical University General Hospital
Contact	Guolin Wang, MD, PhD
Phone	+8618604755166
Email	wangguolinghad@hotmail.com
Status	Not yet recruiting
Phase	N/A
Start date	May 3, 2024
Completion date	October 10, 2024

View Details

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