Melatonin Studies of Totally Blind Children

Sleep Disorder Clinical Trial

Official title: Melatonin Studies in Young Blind Children and Adolescents

Status Terminated

Clinical Trial Summary

The purpose of this study is to learn more about abnormal body rhythms in blind boys and girls that keep them from falling asleep at bed-time or cause them difficulty staying alert during the day. The investigators hope to learn if there are any differences between the body rhythms of girls and boys. The investigators also want to investigate whether age or puberty have an effect on body rhythms.

Clinical Trial Description

Subjects will be asked to collect saliva samples in their home hourly throughout the daytime, approximately every 2 weeks. Subjects may be monitored for up to a year, after which they will be discontinued from the study. If subjects are found to be naturally entrained to the 24-hour day, they will be monitored longitudinally for changes. Subjects will be discontinued after their monitoring period is over or after an entrained status has been confirmed. While no specific time commitment is required, we hope most subjects will participant for 4 months - 2 years. ;

Related Conditions & MeSH terms

• Blindness
• Sleep Disorder
• Sleep Wake Disorders

• NCT number: NCT00795236
• Study type: Interventional
• Source: Oregon Health and Science University
• Status: Terminated
• Phase: N/A
• Start date: November 2009
• Completion date: June 2015