Understanding Sleep in Hospitalized Older Patients

Sleep Deprivation Clinical Trial

Official title:

Environment and Perceived Control: Improving Sleep in Hospitalized Older Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01057823
• Other study ID #: 16685B
• Secondary ID: 1K23AG033763-01
• Status: Completed
• Start date: January 2010
• Est. completion date: July 19, 2020

Study information

• Verified date: May 2021
• Source: University of Chicago
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The overall goal of this research is to elucidate how environmental, healthcare, and patient-level factors and patients' level of perceived control impact sleep duration and quality in hospitalized older patients and to assess whether better in-hospital sleep is associated with improved physical activity and health outcomes.

We hypothesize that environment, healthcare disruptions and patient symptoms will be significantly associated with objective and subjective sleep duration and sleep quality in hospitalized older patients.

We also hypothesize that a high level of perceived control will be associated with improved sleep duration and quality in hospitalized older patients.

We further hypothesize that shorter sleep duration and quality in hospitalized older adults will be associated with adverse health outcomes, namely higher blood pressure and blood sugar.

Description:

This research can lead to a better understanding of the effects of inpatient sleep on health outcomes for hospitalized older patients and can help inform the design and evaluation of interventions designed to improve sleep in hospitalized older patients. This work can also form the foundation for understanding the longer term health effects of inpatient sleep loss for older patients that are potentially modifiable.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 771
• Est. completion date: July 19, 2020
• Est. primary completion date: July 19, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

• Age 50 or above

• Hospitalized on General Medicine service

• Ambulatory

• Community Dwelling

• MMSE >17

Exclusion Criteria:

• transfer from the ICU or another hospital

• cognitively impaired

• not ambulatory

• residents of a nursing home or skilled nursing facility

• on bedrest

• documented sleep disorder in their medical history

Related Conditions & MeSH terms

• Sleep Deprivation
• Sleep Fragmentation

Locations

Country	Name	City	State
United States	The University of Chicago Medical Center	Chicago	Illinois

Sponsors (2)

Lead Sponsor	Collaborator
University of Chicago	National Institute on Aging (NIA)

Country where clinical trial is conducted

United States, 

References & Publications (3)

Adachi M, Staisiunas PG, Knutson KL, Beveridge C, Meltzer DO, Arora VM. Perceived control and sleep in hospitalized older adults: a sound hypothesis? J Hosp Med. 2013 Apr;8(4):184-90. doi: 10.1002/jhm.2027. Epub 2013 Mar 18. — View Citation

Arora VM, Chang KL, Fazal AZ, Staisiunas PG, Meltzer DO, Zee PC, Knutson KL, Van Cauter E. Objective sleep duration and quality in hospitalized older adults: associations with blood pressure and mood. J Am Geriatr Soc. 2011 Nov;59(11):2185-6. doi: 10.1111 — View Citation

Yoder JC, Staisiunas PG, Meltzer DO, Knutson KL, Arora VM. Noise and sleep among adult medical inpatients: far from a quiet night. Arch Intern Med. 2012 Jan 9;172(1):68-70. doi: 10.1001/archinternmed.2011.603. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Sleep will be measured using subjective reports (Karolinska Sleep Diary on Daily Sleep Assessment).		January 2010-January 2015
Secondary	Sleep will also be measured objectively using actigraphy.		January 2010-January 2015