Clinical Trials Logo

Clinical Trial Summary

Negative expiratory pressure is a technique that has been the focus of many studies in the last few years.

Airway response to the application of a negative expiratory pressure (NEP) can be used to detect the presence of upper airway collapsibility. In normal subjects, an increase in expiratory flow is observed while in patients with collapsible upper airway, the flow will show a transient decrease due to airway collapse.

The objectives of this study will be initially to investigate the diagnostic utility of this technique as a noninvasive measurement of the stability of the upper airway in sleep-related breathing disorders. Secondly, we aim to see the sites of airway obstructions, discovered by NEP, through nasal endoscopy. Finally, we aim at testing the utility of NEP technique in the evaluation of therapeutic response. For this purpose, we will apply it in patients before and after airway stabilization interventions like ENT surgery, oropharyngeal exercises, orthodontic mandibular advancement electrical stimulation of the hypoglossal nerve.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03893552
Study type Interventional
Source Université Catholique de Louvain
Contact
Status Completed
Phase N/A
Start date March 1, 2016
Completion date December 30, 2016

See also
  Status Clinical Trial Phase
Recruiting NCT05477719 - Effect of Compression Stockings on the Number of Apneas/Hypopneas Per Hour of Sleep in Patients With Syndrome Obstructive Sleep Apnea/Hypopnea as Compared to no Treatment N/A
Completed NCT04979234 - A Single Centre, Prospective Feasibility Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina) on Severe Obstructive Sleep Apnea Syndrome N/A
Terminated NCT02735694 - Cycloserine in the Treatment of Sleep Apnea Phase 1
Active, not recruiting NCT02470182 - Screening for Sleep Disordered Breathing With Minimally Obtrusive Sensors
Completed NCT02088723 - Testing the Elevation as Sleep Apnea Treatment N/A
Completed NCT01457014 - Sleep Disordered Breathing and Chronic Pain N/A
Completed NCT00976417 - Mechanisms of Action of Adaptive Servoventilation N/A
Completed NCT00860743 - Respiratory and Autonomic Plasticity Following Intermittent Hypoxia Early Phase 1
Active, not recruiting NCT00371293 - The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease N/A
Completed NCT00607893 - Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea N/A
Completed NCT00083798 - Family Linkage Study of Obstructive Sleep Apnea (OSA) in Iceland N/A
Completed NCT00070681 - Outcomes of Sleep Disorders in Older Men Phase 3
Completed NCT00089752 - Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea N/A
Completed NCT00051363 - Apnea Positive Pressure Long-Term Efficacy Study Phase 3
Completed NCT00046670 - Sleep Disordered Breathing, APOE, and Lipid Metabolism N/A
Completed NCT00031239 - Sleep Apnea in Look AHEAD Participants - Ancillary to Look AHEAD N/A
Terminated NCT00006321 - Neurocognitive Function in Snoring Children N/A
Completed NCT00006323 - Neurobehavioral Consequences of Sleep Apnea in Children N/A
Completed NCT00005511 - SCOR in Neurobiology of Sleep--Intermediate Traits for Sleep Apnea N/A
Completed NCT00005275 - Sleep Heart Health Study (SHHS) Data Coordinating Center N/A