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Reboxetine for Sleep Apnoea After ENT Surgery — RENTOSA  

Sleep Apnea, Obstructive Clinical Trial

Official title:
Reboxetine for Obstructive Sleep Apnoea After Upper Airway Surgery: a Randomised, Double-blind, Placebo-controlled Study

Clinical Trial Summary

This pilot study will establish the feasibility of a larger trial to investigate whether reboxetine, a medication used to treat depression, can reduce the severity of obstructive sleep apnea (OSA) including increased blood oxygenation in post-surgical OSA patients where positive airway pressure (CPAP) therapy is either frequently poorly tolerated or not an option immediately post surgery. In this randomized, placebo-controlled, double-blind study, participants will use at-home sleep monitoring equipment before and after surgery plus measures of oxygenation. They will be prescribed either reboxetine or a placebo for seven days after surgery and complete questionnaires at the beginning and end of the study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05978505
Study type Interventional
Source Flinders University
Contact Emma J Thomas
Phone +61 8 8201 2912
Email ethomas@flinders.edu.au
Status Not yet recruiting
Phase Phase 2
Start date August 15, 2023
Completion date December 2024
View Details
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