Sleep Apnea, Obstructive Clinical Trial
Official title:
Prescision Medicine in Obstructive Sleep Apnea, Cardiovascular and Cerebrovascular Disease: AI Electrocardiogram Patch Does it All
Obstructive Sleep apnea(OSA) is a disease with multiple causes, and treatments are very diverse. Patients and doctors have a lot of choices. The concept of precision medicine is needed to intervene so that doctors and patients can have directions in this huge map and won't get lost. In this OSA maze, we have already walked through some feasible passages, but we are far from reaching the end. At present, the research direction of artificial intelligence for OSA is mostly focused on how to accurately screen, but less attention is paid on how to accurately treat and conveniently follow the effectiveness of treatment to increase patient compliance. We can already analyze the results of electrocardiogram patches to predict the severity of sleep apnea. We have also been able to analyze the results of electrocardiogram patches for three consecutive nights, and found postural sleep apnea that could not be detected in laboratory sleep examinations, and help doctors provide appropriate intervention to improve patients' sleep apnea, severity and quality of sleep. We have also found that precision sleep endoscopy can be used to predict the outcome of sleep apnea patients after surgery and the effectiveness of treatment with an intraoral nagative airway pressure device. Therefore, in the future, with artificial intelligence(AI), ECG patches are able to be used for follow patients' treatment effectiveness. Others include the treatment of weight loss drugs and bariatric surgery for obese patients, the control of environmental temperature and humidity, and the training of oropharyngeal and tongue muscle strength, all of which require the diagnosis and follow up of AI ECG patches from beginning to end. According to the latest research, nocturnal hypertension is more relevant to the prognosis of cardiovascular problems and cerebrovascular disease that may occur in the future. This is also the problem that we are most concerned about in the treatment of sleep apnea. ECG patches also have the potential to provide us with information about nocturnal hypertension. Studies have also shown that ECG patches test results are highly correlated with nocturnal hypertension. Therefore, the improvement of nocturnal hypertension can also be used as an important indicator of the effectiveness for our treatment of sleep apnea. Therefore, the goal of this project is to develop AI algorithm to make ECG patches more helpful to patients with sleep apnea, and to make better treatment decisions that are most suitable for patients, such as postural therapy, bariatric surgery for obese patients, environmental temperature and humidity control, oropharyngeal tongue muscle strength training, and accompany with sleep endoscope for the selection of intraoral negative pressure devices and surgery, and finally use AI ECG patches for the patient for three consecutive nights to evaluate the improvement of nocturnal hypertension and sleep apnea, and to achieve the goal of precision medicine in OSA.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT03605329 -
Evaluation of the Severity of Cardiovascular Autonomic Neuropathy in Type 1 Diabetic Patients With OSAS
|
N/A | |
| Completed |
NCT04912635 -
Evaluation of a Health Dashboard Intervention to Improve Engagement With CPAP Therapy in PAP-Naïve Patients: Project Neo
|
N/A | |
| Not yet recruiting |
NCT05939934 -
Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal
|
N/A | |
| Enrolling by invitation |
NCT02290236 -
Monitored Saturation Post-ICU
|
N/A | |
| Completed |
NCT02088723 -
Testing the Elevation as Sleep Apnea Treatment
|
N/A | |
| Terminated |
NCT02269774 -
Origin of Premature Atrial Beats Induced by Simulated Obstructive Sleep Apnea
|
N/A | |
| Completed |
NCT02261857 -
3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea
|
Early Phase 1 | |
| Completed |
NCT01181570 -
Efficacy and Safety of Adalimumab in Patients With Psoriasis and Obstructive Sleep Apnea
|
Phase 4 | |
| Completed |
NCT01943708 -
Novel Auto-continuous Positive Airway Pressure (CPAP) Validation
|
Phase 3 | |
| Completed |
NCT00273754 -
The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).
|
Phase 2 | |
| Recruiting |
NCT02166879 -
Undetected Sleep Apnea in the Postanesthesia Acute Care Unit (PACU)
|
||
| Recruiting |
NCT04963192 -
Integrated Management of Chronic Respiratory Diseases
|
N/A | |
| Completed |
NCT04846400 -
Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
|
N/A | |
| Completed |
NCT05056766 -
How Does the Clinical and Paraclinical Efficacy of an Oral Appliance Evolved According to Propulsion: Control With Each mm of Advancement
|
||
| Recruiting |
NCT04314492 -
Intracapsular Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults
|
N/A | |
| Completed |
NCT05175287 -
OSA (oRisk of Obstructive Sleep Apnea and Traffic Accidents Among Bus Drivers in Ecuador: is There a Significant Association
|
||
| Active, not recruiting |
NCT03431038 -
Cross-sectional Study of Prevalence Rate of Abdominal Aortic Aneurysm in OSAHS Patients From BTCH
|
N/A | |
| Enrolling by invitation |
NCT03075787 -
Cardiovascular Variability and Heart Rate Response Associated With Obstructive Sleep Apnea
|
N/A | |
| Completed |
NCT03300037 -
HYpopnea and Apnea Detection and Treatment Performance of a New cardiOreSpiratory Holter Monitor
|
N/A | |
| Recruiting |
NCT06097949 -
AcuPebble to Remotely Monitor Patients With OSA on CPAP Therapy
|