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Skull Base Neoplasms clinical trials

View clinical trials related to Skull Base Neoplasms.

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NCT ID: NCT03972514 Active, not recruiting - Brain Tumor Clinical Trials

Observational Trial of the Impact of Radiation Dose in Children With Brain and Skull Base Tumors.

Start date: March 8, 2019
Phase:
Study type: Observational

This is a prospective, observational clinical trial investigating the morphological and volumetric changes in the brain following cranial Radiation Therapy in pediatric patients with brain or skull base tumors.

NCT ID: NCT03448614 Active, not recruiting - Clinical trials for Skull Base Neoplasms

Skull Base Reconstruction After Endonasal Cranio-endoscopic Resection Using Autologus Grafts

Start date: January 1, 2018
Phase: N/A
Study type: Observational

Endonasal endoscopic approach to the skull base has been expanded in the last several years owing to advances in the radiological aspect that provided a better evaluation of the lesions and the surrounding structures, technological advances that include angled endoscope, development of high-resolution cameras, high definition monitors and navigation systems and better anatomical experience. The endoscopic endonasal approach now provides access to frontal sinus to the second cervical vertebra in the sagittal plane and from the sella to the jugular foramen in the coronal plane. Endoscopic resection of large skull base tumors results in large defect for which repair is a challenge. Several factors besides the size of the defect should be considered during skull base repair as CSF leak, CSF pressure, history or need for future radiotherapy, lack of support and local tissue vascularity. The aim of this study is to Provide an algorithmic approach for skull base reconstruction after endonasal cranio-endoscopic resection using autologous grafts according to the extent of resection, skull base defect size, the presence of CSF leak, CSF pressure and local tissue vascular