Prospective Evaluation of Topical Almond Oil vs Hydroquinone

Skin Pigmentation Clinical Trial

Official title: Prospective Evaluation of Topical Almond Oil vs Hydroquinone on the Appearance of Facial Pigmentation and the Stability of the Microbiome

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to analyze facial pigmentation and skin microbiome changes after topical almond oil application, compared to the use of topical hydroquinone.

Clinical Trial Description

The purpose of this experiment is to analyze facial pigmentation and skin microbiome changes after topical almond oil application, compared to the use of topical hydroquinone.

There will be a total of 50 subjects:

• 25 randomized to receive almond oil nightly

• 25 randomized to receive 2% hydroquinone nightly

Study Timelines:

• The duration of an individual subject's participation will last from the day of the consent/screening (visit 1) until visit 5 where they will have images taken and measurements collected to assess skin pigment, skin hydration, sebum excretion rate.

• The duration of participation is 4 months.

• The estimated time for the investigators to complete primary analysis is 2 years. ;

Related Conditions & MeSH terms

• Skin Pigmentation

• NCT number: NCT04875715
• Study type: Interventional
• Source: University of California, Davis
• Status: Active, not recruiting
• Phase: Phase 4
• Start date: July 1, 2021
• Completion date: August 1, 2023