Effect of Oral Collagen Tripeptide on Skin Moisture and Wrinkles in Adult Women

Skin Manifestations Clinical Trial

Official title:

Effect of Oral Collagen Tripeptide on Skin Moisture and Wrinkles in Adult Women

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03505684
• Other study ID #: 02-2017-033
• Status: Completed
• Phase: N/A
• Start date: December 24, 2017
• Est. completion date: July 30, 2018

Study information

• Verified date: August 2018
• Source: Pusan National University Yangsan Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Comparison of a randomized, double-blind, and control-group study for the effect of oral ingestion of collagen tripeptides derived from fish on dermal moistures and wrinkles body fat reduction in participants

Description:

The aim is to investigate the effect of oral ingestion of collagen tripeptides derived from fish on dermal moistures and wrinkles body fat reduction in participants by a randomized, double-blind, and control-group study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 84
• Est. completion date: July 30, 2018
• Est. primary completion date: July 15, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 40 Years to 60 Years

Eligibility

Inclusion Criteria:

• > = 4 of Tewameter

Exclusion Criteria:

• Within the last 6 months, took skin surgery including cosmetic purpose

• Diabetic patients with poor glycemic control with a fasting blood glucose of 160 mg/dl or more

• Creatinine levels: more than twice the normal upper limit

• AST (GOT) or ALT (GPT) levels: more than twice the normal upper limit

• Uncontrolled hypertension

• sun allergy or sensitive skin

• functional cosmetics that affect dermal moistures and wrinkles within the last 3 months.

• If you have participated or are planning to participate in another clinical trial within the past month

• Alcohol abuser

• If they are pregnant or lactating or have a pregnancy plan during the clinical trial Those with allergic reactions to the constituent food

• Any person deemed inappropriate by the researcher for other reasons

Related Conditions & MeSH terms

• Skin Manifestations
• Skin Wrinkling

Intervention

Dietary Supplement:
• CTP
1,000 mg of CTP was orally administered per day for 12 weeks.
• placebo (starch)
placebo (starch)

Locations

Country	Name	City	State
Korea, Republic of	Integrated Research Institute for Natural Ingredients and Functional Foods	Yangsan

Sponsors (1)

Lead Sponsor	Collaborator
Pusan National University Yangsan Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes in Transepidermal Waterloss by Tewameter	comparison between baseline, after 6 weeks, and after 12 weeks	baseline, after 6 weeks, and after 12 weeks
Secondary	changes in skin wrinkling indices by Visiometer	comparison between baseline, after 6 weeks, and after 12 weeks	baseline, after 6 weeks, and after 12 weeks
Secondary	skin elasticity by Cutometer	comparison between baseline, after 6 weeks, and after 12 weeks	baseline, after 6 weeks, and after 12 weeks
Secondary	changes in hydration level of the skin surface by Corneometer	comparison between baseline, after 6 weeks, and after 12 weeks	baseline, after 6 weeks, and after 12 weeks