Effect of Vitamin D After Application With Valchlor

Skin Irritation Clinical Trial

Official title: The Effect of Oral Vitamin D (Cholecalciferol) Supplementation After Topical Application With Valchlor

Status Completed

Clinical Trial Summary

The purpose of this research study is to evaluate the effects of an oral Vitamin D on the body's immune system.

An interest has been growing because studies have shown that Vitamin D may reduce inflammation and harmful effects in the body, however, the best dose for Vitamin D is still unknown.

Inflammation is the body's physical response to infection, injury, or long term disease. Pain, redness, heat, and sometimes loss of function are all signs of inflammation in the body. This study will look at product use, testing skin irritation in healthy volunteers and seeing how Vitamin D may help stop or reduce inflammation and skin irritation, which could one day help doctors prescribe Vitamin D to patients with long term disease to relieve their symptoms.

Clinical Trial Description

Primary Endpoint To determine the effect of a topical application of Valchlor on human subjects at the clinically approved dose.

Secondary Endpoint To establish the efficacy of cholecalciferol (vitamin D3) in reducing skin irritation 48 hours after topical application of Valchlor. ;

Related Conditions & MeSH terms

• Skin Irritation

• NCT number: NCT02968446
• Study type: Interventional
• Source: University Hospitals Cleveland Medical Center
• Status: Completed
• Phase: Early Phase 1
• Start date: November 17, 2016
• Completion date: October 1, 2018