Skin Diseases Clinical Trial
Official title:
Red Low Level LASER Versus Narrow Band Ultraviolet B in the Treatment of Facial Acne Vulgaris
Forty-five participants with facial AV were assigned randomly to three groups of fifteen subjects each. Each group received various therapies. Group A (Study group A) had received both NBUB and akne-Mycin; Group B( study group B) had received Red LLLT and akne-Mycin and group C (Control group) received only akne-Mycin cream. All 45 participants are tested at the initial treatments, after 4 weeks and after 8 weeks by the acne count, the intensity scale and the photographic test.
Forty-five patient (18 male and 27 female) were recruited on a referral basis from the
department of dermatology at Kasr Al- aini Teaching Hospital. Firstly, an interview was held
with each participant to determine gender, age, skin type, acne severity and medical
prescriptions,Randomization was performed by selecting numbers from opaque envelopes
containing numbers that were chosen by a random number generator, selection was done by an
independent person.
Patients in group (A) received a program of NBUB, ( DIXWELL EMLY 98 -ABRP 64 ,made in France)
wavelength 311 to 313nm , in addition to topical aknemycin medications. Each treatment lasts
one to eight minutes. The treatments were given three times a week. for 8 weeks.Participants
in-group (B) received a program of R-LLLT that was conducted through laser equipment InGaAs
(630 nm, 10 mW, continuous) (RIKTA, Russia) with fluence 12 J/cm2, two sessions per week for
8 weeks .Patients in the three groups were asked to apply topical erythromycin cream 2%
(Akne-Mycin- Egypt) two times per day on the entire face from the beginning to the end of the
treatment period .Evaluation was based on formal counts of active lesions (papule and
pustule).facial photographs using a digital camera (PANASONIC, Tokyo, Japan). and Five-point
scale of investigators assessment that reflect lesion count improved percentage.
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