Skin Cancer Clinical Trial
Official title:
VivaNet Study. A Multicenter Study of Confocal Reflectance Microscopy in Telemedicine
The goal of this study is to test a protocol that uses clinical pictures, confocal reflectance microscopy images and dermoscopic information in a telemedicine platform. This protocol will test the technologies and diagnostic performance of dermoscopy and confocal reflectance microscopy in a randomized prospective multicenter study in five different centers in Europe.
In vivo confocal reflectance microscopy (CRM) is a non-invasive method for the in vivo
(without cutting into the skik) examination of skin tumors. CRM produces cellular images with
resolution comparable to histopathology. The procedure is painless, takes about ten minutes
and has no documented side effects. Studies performed in the past decade have correlated CRM
features in benign (non-cancerous) and malignant (cancerous) skin lesions such as moles and
melanomas, as well as features of inflammatory lesions (such as allergic skin reactions) to
histopathology.
Dermoscopy is a complementary technique that has been proven to be superior to the naked eye
for the diagnosis of melanoma as well as some non-melanocytic skin tumors. Recently,
correlation of dermoscopic and CRM structures has focused interest in the research in
different groups that show that both are complementary and render in combination a better
understanding of skin disease.
In this study, patients from several research centers in Europe, with lesions suspicious for
malignancy and scheduled for biopsy will be asked if they would like to participate in the
study. If they consent to the study, first, a clinical photograph will be taken of the
lesion. Second, a dermoscopic image will be taken of the lesion, and third, CRM images will
be taken of the lesion. Finally, the biopsy will be performed as per the standard of care.
The images will be sent over a secure, private internet connection to physicians specially
trained in the interpretation of dermoscopic and CRM images. An electronic report will be
completed and returned to the Study Coordinator, who will correlate the results with the
histopathologic diagnosis.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT02721459 -
XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma
|
Phase 1 | |
Completed |
NCT03740815 -
Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection
|
N/A | |
Recruiting |
NCT05779423 -
Cryoablation+Ipilimumab+Nivolumab in Melanoma
|
Phase 2 | |
Terminated |
NCT01468818 -
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
|
Phase 2 | |
Completed |
NCT01820234 -
Evaluation of Store-and-Forward Teledermatology Versus a Face-to-Face Assessment During a Skin Cancer Screening Event
|
N/A | |
Completed |
NCT00535769 -
Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
|
Phase 0 | |
Completed |
NCT00526032 -
Melanoma Detection by Oblique-Incidence Optical Spectroscopy
|
N/A | |
Completed |
NCT00588341 -
Phase II Trial of Neoadjuvant Temozolomide in Melanoma Patients With Palpable Stage III or IV Disease Undergoing Complete Surgical Resection
|
Phase 2 | |
Active, not recruiting |
NCT01447199 -
The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)
|
||
Enrolling by invitation |
NCT04758988 -
AI Augmented Training for Skin Specialists
|
N/A | |
Not yet recruiting |
NCT04534868 -
Patient Acceptance And Satisfaction of Teledermoscopy In General Practice In a Belgian Rural Area
|
N/A | |
Recruiting |
NCT04138342 -
Topical Fluorescent Nanoparticles Conjugated Somatostatin Analog for Suppression and Bioimaging Breast Cancer
|
Phase 1 | |
Completed |
NCT03673917 -
Cosmetology Students and Skin Cancer
|
N/A | |
Recruiting |
NCT04341064 -
Sun-safe Habits Intervention and Education
|
Phase 3 | |
Completed |
NCT04206995 -
Cancer Sensing: Evaluation of Odour Sampling Techniques
|
||
Recruiting |
NCT05574101 -
A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer
|
Phase 2 | |
Not yet recruiting |
NCT05860881 -
Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)
|
Phase 3 | |
Completed |
NCT05146622 -
Virtual Sun Safe Workplaces Ph I
|
||
Recruiting |
NCT05068310 -
Applicability of a Cellular Resolution Full-field OCT Image System for Pigmented and Non-pigmented Skin Tumors
|
||
Recruiting |
NCT03889899 -
Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.
|
N/A |