Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

Skin Burn Multiple Clinical Trial

Official title:

Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01166893
• Other study ID #: 20097322
• Secondary ID: R01GM108634
• Status: Recruiting
• Start date: March 2010
• Est. completion date: February 2026

Study information

• Verified date: December 2023
• Source: University of California, Irvine
• Contact: Gordon Kennedy, PhD
• Phone: 949-824-4713
• Email: gordon.kennedy[@]uci.edu
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

According to the National Burn Repository 2007, the most common type of burn injury is a partial thickness burns. The current standard of care for partial thickness burns is two weeks of topical therapy and wound care. Burns that do not heal within two weeks undergo surgical excision and skin grafting.

Description:

Researcher can use the combination of Modulated Imaging and Laser Speckle Imaging can be used as an adjuvant to standard clinical evaluation to gauge burn wound and severity of infection. Researcher can image the burn wounds of and compare with current standard of care, clinical exam, and can use the outcomes information in terms of time to healing and treatment

Modulating Imaging is a noninvasive optical modality measure the metabolic functions of the burn wound.

Laser Speckle Imaging is a noninvasive optical modality can measure blood flow of burn wound.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: February 2026
• Est. primary completion date: February 2026
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Minute and older

Eligibility

Inclusion Criteria:

1. Male / female all age

2. Subjects is an inpatient or out patient with burn wound

Exclusion Criteria:

1. Subjects cannot lied flat and still for the duration of the imaging

2. Subjects pregnant.

Related Conditions & MeSH terms

• Burns
• Skin Burn Multiple

Intervention

Device:
• Modulated Imaging and Laser Speckle Imaging
wound healing

Locations

Country	Name	City	State
United States	UCIMC	Orange	California

Sponsors (2)

Lead Sponsor	Collaborator
University of California, Irvine	National Institute of General Medical Sciences (NIGMS)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Noninvasive burn wound severity assessment	Noninvasive burn wound severity assessment using noncontact optical device	1 day