Clinical Trials Logo
  1. Home
  2. SIRS
  3. NCT02079597

The Role of Ninjurin-1 During Systemic Inflammation — Ninj1  

SIRS Clinical Trial

Official title:
Prospective Study to Analyze Ninjurin-1 and Its Soluble Part During Systemic Inflammation

Clinical Trial Summary

- With the underlying study the investigators address the question if Ninjurin-1 (Ninj1) expression is altered in patients with systemic inflammatory response syndrome (SIRS) in comparison to healthy volunteers.

- The adhesion molecule Ninj1 is induced following nerve injury where it contributes to nerve generation. Besides it is described to facilitate leukocyte migration especially in the nervous system.

- The investigators hypothesize that Ninj1 expression is increased in SIRS patients, which will fortify its impact during inflammation and the transferability from bench to bedside.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02079597
Study type Observational
Source Johann Wolfgang Goethe University Hospitals
Contact
Status Completed
Phase N/A
Start date February 2014
Completion date September 2014
View Details
See also
  Status Clinical Trial Phase
Terminated NCT04117568 - The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients
Completed NCT01686776 - A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA Phase 3
Recruiting NCT02922998 - CD64 and Antibiotics in Human Sepsis N/A
Completed NCT02083198 - Effects of IV Chloride Content on Outcomes N/A
Completed NCT01410578 - The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO N/A
Recruiting NCT05023954 - mSEP: Testing of Physiological and Immune-metabolic Blood Markers for Maternal Sepsis
Completed NCT00554021 - Infections Related Central Venous Catheters N/A
Not yet recruiting NCT05142813 - A Blood Test to Diagnose Sepsis in Symptomatic Adults and Children
Recruiting NCT01493466 - Serum Proteomics Analysis for Sepsis N/A
Recruiting NCT01493492 - Urinary Proteomics Analysis for Sepsis and Prognosis N/A
Recruiting NCT01155674 - Innate Immune Functions of Immature Neutrophils N/A
Completed NCT01333657 - The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries N/A
Completed NCT01236703 - Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU N/A
Not yet recruiting NCT03082469 - Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal Phase 4
Terminated NCT02704871 - The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS N/A
Completed NCT04901338 - Cytokine Hemoadsorption in ECMO Patients
Completed NCT01585909 - Evaluation of Intestinal Brush Border Enzyme Function in Critically Ill Patients N/A
Completed NCT01649440 - Sepsis Metabolomics N/A
Completed NCT03784521 - Efficacy of Intravenous In-line Filter in Patient Undergoing Cardiac Surgery N/A
Completed NCT04724044 - Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia Phase 3