Losartan to Reverse Sickle Nephropathy

Status Completed

Clinical Trial Summary

Sickle cell disease causes kidney damage with increasing age, leading to chronic kidney disease and renal failure in nearly one third of patients with sickle cell disease. Currently, there is no treatment for sickle cell related kidney disease.

Clinical Trial Description

The purpose of this research study is to see if losartan can help reduce or reverse damage done to the kidneys of children and adults with Sickle Cell Anemia (SCA) and Sickle Beta-zero (HbSβ0) Thalassemia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01479439
Study type	Interventional
Source	Children's Hospital Medical Center, Cincinnati
Contact
Status	Completed
Phase	Phase 2
Start date	February 2012
Completion date	December 2015

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See also
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