Sickle Cell Anemia Clinical Trial
Official title:
Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects.
Patients suffering from Thalassemia or another hemoglobinopathies required regular blood
transfusions. The complications and adverse effects of blood transfusions can be classified
as immediate and late. Among the immediate effects the most common are allergic reactions
and fever, besides congestive heart failure in patients with cardiomyopathy. The late
effects are mostly related to blood transmitted infections like HIV or Hepatitis C
infections.
The purpose of this study is to summarize the data of those complications in a cohort of 100
patients receiving regular blood transfusion.
About 100 patients aged several months to 50 years are treated in the Pediatric Hematology
Unit, most of those patients receive blood transfusions monthly. The adverse reactions were
routinely recorded during each transfusion. All the patients were also screened annually for
the incidence of blood transmitted infections principally HIV and Hepatitis C. All those
records will be systematically screened and all the immediate or late adverse reactions and
complications related to blood transfusions will be summarized.
A second goal of this study will be to control the staff strictness related to the ministry
of health protocol dealing to blood transfusions.
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Observational Model: Case-Only, Time Perspective: Retrospective
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