Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine whether intra-articular botulinum toxin type A is effective in the treatment of chronic joint pain.

Clinical Trial Description

Chronic shoulder pain unresponsive to oral medications and intra-articular corticosteroids is an important treatment problem, especially for the young, very old and those with complex medical problems that preclude joint reconstructive surgery. We hypothesized that intra-articular botulinum toxin could provide important joint pain relief in these patients. This is a prospective, double blined, placebo controlled 6month trial with an open label extension phase when pain returns to baseline levels (re-injection with 100units of botulinum toxin and 6 months followup thereafter).

Comparisons: Intra-articular injection of botulinum toxin type a will be compared to intra-articular injection of placebo ( lidocaine then saline). ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00211718
Study type	Interventional
Source	Minneapolis Veterans Affairs Medical Center
Contact	Maren L Mahowald, MD
Phone	6124674190
Email	mahow001@umn.edu
Status	Recruiting
Phase	Phase 3
Start date	July 2004
Completion date	June 2007

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