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NCT03155126 Clinical Trial

Different Crystalloids on AKI in Shock

Shock Clinical Trial

Official title:
The Effect of Different Crystalloids on the Incidence of Acute Kidney Injury in Shock Patients

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT03155126
Other study ID # 2017ZDSYLL017P01
Secondary ID
Status Enrolling by invitation
Phase N/A
First received May 11, 2017
Last updated June 13, 2017
Start date June 2017
Est. completion date July 2018

Study information
Verified date June 2017
Source Southeast University, China
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Description:

Fluid resuscitation is important to shock patients. Saline is the classical fluids for resuscitation. However, studies showed that resuscitation with saline could increase the incidence of hyperchloremia and acute kidney injury. Thus, the goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 600
Est. completion date July 2018
Est. primary completion date June 2018
Accepts healthy volunteers
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria:

- Shock patients who need fluid resuscitation with risk factors of acute kidney injury

Exclusion Criteria:

- Patients with a history of chronic kidney injury and hemodialysis therapy

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Fluid resuscitation
Patients in the saline group were resuscitated with saline, patients in the other group were resuscitated with acetated Ringer's sodium

Locations
Country Name City State
China Zhongda Hospital Southeast University Nanjing Jiangsu

Sponsors (1)
Lead Sponsor Collaborator
Southeast University, China

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary Incidence of acute kidney injury Incidence of acute kidney injury 28 day
Secondary Application of renal replacement Application of renal replacement 28 day
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