Sexually Transmitted Diseases Clinical Trial
Official title:
Clinical Study to Investigate the Effect of Doxycycline, Pentoxifylline, and Nitazoxanide in Sexually Active Men
Verified date | June 2023 |
Source | Tanta University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Bacterial sexually transmitted infections (STIs) have been steadily increasing in gay, bisexual, and other men who have sex with men (MSM) over the past 2 decades. While that trend started prior to the introduction of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) in 2012, HIV PrEP has been associated with increases in sexual contacts and decreases in condom use with an resultant acceleration in the increase of bacterial STIs such as gonorrhea, syphilis, and chlamydia.
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | June 20, 2028 |
Est. primary completion date | June 20, 2024 |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 18 Years to 60 Years |
Eligibility | Inclusion Criteria: - Individuals aged > 18 years were eligible for participation if they had a diagnosis of untreated gonorrhea and chlamydia. The untreated status was defined as no antibiotic taken in the previous 28 days to treat gonorrhea and chlamydia. Exclusion Criteria: - known contraindications or hypersensitivity to doxycycline, pentoxifylline, and nitazoxanide. gonorrhea with complications, such as pelvic inflammatory disease or epididymo-orchitis significant renal failure or hepatic failure. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Tanta University | Marwa Ahmed El-Samongy Dermatology and Venereology Department, Tanta University., Mostafa Mahmoud Bahaa Clinical Pharmacy Department, Horus University, New Damietta, Egypt |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | treatment of chylamdia in sexually active men | treatment of chylamdia in sexually active men and decreasing resistance to antibiotics | 1 month |
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