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NCT03960203 Clinical Trial

Effect of a Sepsis Prediction Algorithm on Clinical Outcomes

Severe Sepsis Clinical Trial

Official title:
Effect of a Sepsis Prediction Algorithm on Patient Mortality, Length of Stay, and Readmission

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03960203
Other study ID # 05172019
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date January 2017
Est. completion date June 2018

Study information
Verified date May 2019
Source Dascena
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

In this clinical outcomes analysis, the effect of a machine learning algorithm for severe sepsis prediction on in-hospital mortality, hospital length of stay, and 30-day readmission was evaluated.

Description:

Materials and Methods: Clinical outcomes evaluation performed on a multiyear, multicenter clinical data set of real-world data containing 75,147 patient encounters from nine hospitals. Mortality, hospital length of stay, and 30-day readmission analysis performed for 17,758 adult patients who met two or more Systemic Inflammatory Response Syndrome (SIRS) criteria at any point during their stay.

Recruitment information / eligibility
Status Completed
Enrollment 75147
Est. completion date June 2018
Est. primary completion date June 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- All patients over the age of 18 presenting to the emergency department or admitted to an inpatient unit at the participating facilities were automatically included for clinical outcomes analysis

Exclusion Criteria:

- Patients under the age of 18

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• InSight
Clinical decision support (CDS) system for severe sepsis detection and prediction

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Dascena

Outcome
Type Measure Description Time frame Safety issue
Primary In-hospital mortality Rate of in-hospital mortality based on SIRS criteria 1 year
Secondary Hospital length of stay Duration of hospital length of stay in days based on SIRS criteria 1 year
Secondary 30-day readmissions Rate of patient readmissions within 30 days 1 year
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