Severe Mood Dysregulation Clinical Trial
Official title:
Interpersonal Psychotherapy for Youth With Severe Mood Dysregulation- Randomized Trial
The purpose of this study is to determine the feasibility and acceptability of utilizing an
adapted form (i.e. IPT-MBD) of a psychosocial intervention, Interpersonal Psychotherapy for
Depressed Adolescents, for youth with severe mood dysregulation (SMD) or disruptive mood
dysregulation disorder (DMDD).
The investigators hypothesize that retention rates will be >80%, satisfaction scores will
average 6 (high) on a 7 point satisfaction scale, and that youth who receive the IPT
intervention will have overall improvement in SMD/DMDD symptoms.
This research is being done to learn more about how to help teenagers with a sad or angry
mood, and emotional responses out of proportion to what would be expected in a situation.
Together these symptoms are called Severe Mood Dysregulation (SMD), a research diagnosis, or
disruptive mood dysregulation disorder (DMDD), a newer clinical diagnosis. Currently, there
is no standard treatment for teens that have SMD/DMDD. These teens usually receive
medication and some type of talk therapy. This research is being done to compare two types
of talk therapy to see which is most effective in helping teens with SMD/DMDD. Investigators
will compare treatment as usual (TAU) with Interpersonal Psychotherapy for Youth with Mood
and Behavior Dysregulation (IPT-MBD). Investigators do not know if TAU and IPT-MBD work just
as well, or if one is better than the other. When this study is over, investigators hope
there will be a better idea of how to study treatments for teens with SMD/DMDD.
For those participants who receive IPT-MBD, are prescribed an antipsychotic, and have
significant improvement in symptoms, investigators will gradually taper the antipsychotic
dose.
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Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01591564 -
Interpersonal Psychotherapy in Youth With Severe Mood Dysregulation-Pilot
|
N/A | |
Completed |
NCT01714310 -
Characterization and Sequential Pharmacotherapy of Severe Mood Dysregulation
|
Phase 2 | |
Enrolling by invitation |
NCT00825552 -
Pharmacological Treatment of Children and Adolescents With Severe Mood Dysregulation
|
N/A |