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Severe Hypoglycemic Unawareness clinical trials

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NCT ID: NCT01897688 Active, not recruiting - Type 1 Diabetes Clinical Trials

A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients

Start date: June 2012
Phase: Phase 3
Study type: Interventional

Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control. The purpose of this study is to determine the safety and effectiveness of islet transplantation, combined with immunosuppressive medications, specifically using Campath as induction, for treating type 1 diabetes in individuals experiencing hypoglycemia unawareness and severe hypoglycemic episodes.