SAM: Discharge Based on the Use of a MUAC-based Criterion to

Severe Acute Malnutrition Clinical Trial

Official title:

Discharge From Community-based Management of Severe Acute Malnutrition Using Mid Upper Arm Circumference

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03303131
• Other study ID #: MUAC 2007-2011
• Status: Completed
• Phase: N/A
• First received: October 2, 2017
• Last updated: February 1, 2018
• Start date: September 1, 2007
• Est. completion date: December 31, 2011

Study information

• Verified date: January 2018
• Source: Epicentre
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Retrospective analysis of routine program data of children aged 6 to 59 months admitted to the MSF therapeutic feeding program with MUAC ≤ 118 mm in Yako and Titao districts of Burkina Faso from 2007-2011.

Description:

Comparison of patient characteristics and treatment outcomes was conducted between two groups: 1) children discharged as recovered from September 2007 to March 2009 with at least 15% of their weight at admission (Period A); and 2) children discharged as recovered from April 2009 to December 2011 with MUAC ≥ 124 mm (Period B).

A total of 50,841 children were admitted with MUAC ≤ 118 mm to the MSF therapeutic feeding program and were included in this analysis: 24,792 children in Period A (2007-2009) and 26,049 children in Period B (2009-2011).

Overall, 89% of admissions were directly into outpatient care and the majority (53%) entered with a MUAC 116-118mm; 48% of children were male and 80% of children < 2 years of age (Table 1).

Compared to children admitted in Period A, children admitted in Period B were statistically more likely to be female, younger, and of better anthropometric status (e.g. higher mean MUAC, WHZ and HAZ).

There was a greater proportion of children admitted directly to inpatient care in Period B than in Period A (10.6% vs 8.0%).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50841
• Est. completion date: December 31, 2011
• Est. primary completion date: December 31, 2011
• Accepts healthy volunteers: No
• Gender: All
• Age group: 6 Months to 59 Months

Eligibility

Inclusion Criteria:

• 6 to 59 months old

• presence of bipedal pitting edema or MUAC = 118 mm

Exclusion Criteria:

• < 6 months old or > 59 months old

• absence of bipedal pitting edema or MUAC = 118 mm

Related Conditions & MeSH terms

• Malnutrition
• Severe Acute Malnutrition

Intervention

Other:
• Discharge from community-based management
Comparison of patient characteristics and treatment outcomes between two groups

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Epicentre	Medecins Sans Frontieres, Netherlands

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	MUAC based criterion	Use of a discharge criterion of MUAC = 124 mm	52 months