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Characterization of Hemostatic Disordres in Septic Shock: Searching for Biological Markers — COASEPT  

Septic Shock Clinical Trial

Official title:
Characterization of Hemostatic Disordres in Septic Shock: Searching for Biological Markers

Clinical Trial Summary

Sepsis induces hemostatic disorders due to the exessive or inappropriate activation of inflammation, which could lead either to hypercoagulability or hypocoagulability. It is currently not possible to determine the hemostatic status of a given patient. This instability of hemostatic system is not revealed by classical tests. Thus, a better characterization of hemostatic status could certainly improve patient care. This study aims at characterizing disorders of coagulation and fibrinolysis using "global" tests such as thrombin generation test or coagulolytic test. Furthermore, the association with biological markers of interest (such as microparticles, neutrophil elastase or histones) will be evaluated.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02692053
Study type Interventional
Source Central Hospital, Nancy, France
Contact Bruno MI LEVY, PhD
Email blevy5463@gmail.com
Status Not yet recruiting
Phase N/A
Start date February 2016
Completion date February 2018
View Details
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