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Echo vs. EGDT in Severe Sepsis and Septic Shock — ECHO RCT  

Septic Shock Clinical Trial

Official title:
Echocardiography-Guided Resuscitation in Severe Sepsis and Septic Shock Vs. Early Goal-Directed Therapy: Pilot Study

Clinical Trial Summary

Echocardiography (cardiac ultrasound) is being used more often in the critical care setting for management of severe infection (septic shock). Early studies show echocardiography to be useful in these patients, but at this time, there are no good clinical trials to justify its use.

Our study goals/objectives are as follows:

1. To conduct an unblinded, two-group randomized controlled clinical trial to compare an echocardiography-guided resuscitation protocol with an Early Goal Directed Therapy (EGDT) protocol in patients with severe sepsis or septic shock.

2. Demonstrate that a sepsis treatment protocol using transthoracic echocardiography and other non-invasive assessments of cardiac output will result in more rapid resolution of septic shock compared to invasive EGDT.

3. Demonstrate patients receiving the non-invasive echocardiography protocol will receive less administration of intravenous fluid.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02354742
Study type Interventional
Source Intermountain Health Care, Inc.
Contact
Status Completed
Phase N/A
Start date December 2014
Completion date October 2017
View Details
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