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NCT02306239 Clinical Trial

The Effect of Terlipressin on Intesitnal Function in Septic Shock Patients

Septic Shock Clinical Trial

Official title:
the Surgical Intensive Care Unit

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02306239
Other study ID # 2012A080204018
Secondary ID
Status Recruiting
Phase N/A
First received December 1, 2014
Last updated December 25, 2014
Start date December 2014

Study information
Verified date December 2014
Source First Affiliated Hospital, Sun Yat-Sen University
Contact liu zimeng, master
Phone 020-87755766
Email sumslzm@163.com
Is FDA regulated No
Health authority China:ethics committee of the first affliated hospitl of Sunyetsen University
Study type Interventional

Clinical Trial Summary

Terlipressin becomes a vasopressin for septic shock. But some studies found it may lead to severe intesitnal complications such as intestinal ischemia. The investigators study was designed to find the effect of terlipressin on intestinal function in septic shock patients.

Recruitment information / eligibility
Status Recruiting
Enrollment 40
Est. completion date
Est. primary completion date August 2015
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- septic shock

Exclusion Criteria:

- shock due to other reasons

- diagnosited intesitinal ischemia

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Terlipressin

• Norepinephrine

Locations
Country Name City State
China the First Affiliated Hospital of Sumyetsan University Guangzhou Guangdong

Sponsors (1)
Lead Sponsor Collaborator
Liu ZiMeng

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary intestinal function assessed by abdominal distension, intestinal bleeding, peritonitis, plasma DAO level, enteral nutrition 7 days Yes
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