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Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis — SAMIRA  

Septic Shock Clinical Trial

Official title:
Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis

Clinical Trial Summary

Use of brain natriuretic peptide to evaluate the cardiac function in the course of meningococcal septic shock or severe sepsis.

Clinical Trial Description

OBJECTIVES: determining sensibility and specificity of BNP blood level to detect myocardial dysfunction in septic shock or severe sepsis due to Neisseria meningitidis in children. METHODS: Prospective multicentric clinical trial including 7 French pediatric intensive care units. Serial cardiac ultra sounds and blood sampling will be done for patients hospitalized for purpura fulminans beginning at the time of admission in pediatric intensive care. Any child from 6 months to 18 years without preexisting cardiac disease and presenting with purpura fulminans will be enrolled after obtaining consent of both parents. From adult's studies on septic shock and BNP, a total number of 30 patients was calculated to be necessary to prove the interest of BNP in this indication. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02041663
Study type Interventional
Source Assistance Publique - Hôpitaux de Paris
Contact
Status Completed
Phase N/A
Start date March 5, 2012
Completion date July 11, 2018
View Details
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