Sepsis Clinical Trial
Official title:
Comparison of Microcirculation Indexes and Hemodynamic Indexes to Guide Early Fluid Resuscitation in Patients With Septic Shock
Comparison of Microcirculation Indexes and Hemodynamic Indexes to Guide Resuscitation in Patients With Septic Shock
Objectives: Comparison of microcirculation indexes and hemodynamic indexes to guide resuscitation in patients with septic shock. Intervention: 1. Microcirculation-oriented resuscitation group: When the system hemodynamics meets the standard of EDGT, the microcirculation-oriented resuscitation group will evaluate the organ perfusion level and adjust the hemodynamic therapy according to the sublingual microcirculation parameters (PPV > 68%). 2. Control group: The standard treatment group will adjust the shock management scheme through systemic hemodynamic parameters. Primary outcome: (1)change in SOFA score at 72h (2)30-day mortality ;
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