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NCT03340649 Clinical Trial

The Predictive Value of Hepatocyte Growth Factor and Soluble Receptor s-Met in Sepsis

Sepsis Clinical Trial

Official title:
The Predictive Value of Hepatocyte Growth Factor and Soluble Receptor s-Met in Evaluating Sepsis Patient's Disease Severity and Prognosis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03340649
Other study ID # 2017ZDSYLL095-P01
Secondary ID
Status Recruiting
Phase N/A
First received November 8, 2017
Last updated November 9, 2017
Start date November 9, 2017
Est. completion date March 1, 2018

Study information
Verified date November 2017
Source Southeast University, China
Contact chenglong liang, master
Phone 15261893562
Email 15261893562@163.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To observe the changes of plasma hepatocyte growth factor and soluble receptor s-Met levels in patients with sepsis, and to explore its clinical significance.

Description:

90 patients who diagnosed as sepsis were included in this study. Then keep blood samples from these patients in the first day, the third day, detect the hepatocyte growth factor and soluble receptor s-Met level in plasma byenzyme-linked immuno sorbent assay. Record Severity of illness and survival status of every patient within 28 days. Objective to evaluate the correlation between the level of hepatocyte growth factor and soluble receptor s-Met in plasma and the prognosis of the patients.

Recruitment information / eligibility
Status Recruiting
Enrollment 90
Est. completion date March 1, 2018
Est. primary completion date November 9, 2017
Accepts healthy volunteers No
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

1. Patients admitted to ICU diagnosed of sepsis(sepsis3.0 criteria)

2. Patients signing informed consent

Exclusion Criteria:

1. Age is less than 18 years old or more than 80 years old

2. Pregnant women

3. Patients with tumor?hepatitis?liver cirrhosis?acute myocardial infarction?chronic renal tubular nephritis?interstitial pneumonia?acute pancreatitis?systemic lupus erythenatosus?ulcerative colitis?crohn's disease?HELLP syndrome

4. Prothrombin time is extension in patients with after liver transplantation

5. Patients with chronic renal failure

6. Patients after kidney transplantation

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• taking peripheral blood
taking peripheral blood of no more than 3ml

Locations
Country Name City State
China Zhongda Hospital Nanjing Jiangsu

Sponsors (1)
Lead Sponsor Collaborator
Jingyuan,Xu

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary mortality 28-day mortality 28-day
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