Sepsis Clinical Trial
Official title:
Plasma Free Fatty Acids in Risk Assessment of Sepsis in the Emergency Department: A Prospective Pilot Study
Verified date | March 2017 |
Source | The Cleveland Clinic |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Plasma free fatty acids (FFAs) are thought to play a role in the generation of organ dysfunction. The investigators hypothesize that plasma FFA levels are a marker of poor prognosis in patients with sepsis. The present study will examine the relation between plasma FFA levels and severity of illness in patients with sepsis presenting to the Emergency Department. It will also examine the relation between plasma FFA levels and the risk of developing late morbidity, multiple organ dysfunction syndrome (MODS) and/or mortality during initial hospitalization and over a 30-day follow-up period.
Status | Completed |
Enrollment | 74 |
Est. completion date | January 2012 |
Est. primary completion date | January 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - 18 years of age or older - Able to provide informed consent (or has surrogate present that can do so) - Presenting to the Emergency Department (ED) for evaluation - Clinical suspicion of infection, as indicated by the ED physician's ordering a blood culture or a current temperature of =38C. Exclusion Criteria: - Liver disease - Hepatitis - Alcohol consumption >2 drinks/day for longer than 6 months - Pregnant women - Prisoners or other institutionalized individuals - Unable to speak the English language - Unwilling or unlikely to be reachable by telephone for the 30-day follow-up status assessment call |
Country | Name | City | State |
---|---|---|---|
United States | Cleveland Clinic | Cleveland | Ohio |
Lead Sponsor | Collaborator |
---|---|
The Cleveland Clinic | Cheetah Medical Inc. |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Disposition: Admission to hospital or discharge home | within 48 h | ||
Primary | Hospital length-of-stay | 30 days | ||
Secondary | All cause mortality | 30 days |
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