Sensorineural Hearing Loss Clinical Trial
Official title:
Evaluation of Listening Effort With Pupillometry in Cochlear Implant Users
Listening with a cochlear implant remains difficult and most listeners will report high levels of listening effort.The present study is a "pilot" aiming to evaluate listening effort for cochlear implant users. The listening effort is measured with pupillometry, by monitoring the variations of pupil size in response to different stimuli. The size of the pupil is known to increase with the listening effort. The listening effort is evaluated in two different situation: speech perception in quiet and speech perception in noise. The pupillometry measures will be compared for the two listening conditions. Moreover, the study will evaluate the relationship between objective (pupil dilatation) and subjective measures (auto evaluation) of listening effort, and between speech comprehension, cognitive abilities and listening effort.
Nowadays, cochlear implants (CI) are successfully used to rehabilitate severe to profound sensorineural hearing loss. Most CI users can understand speech in quiet, but comprehension scores drop in the presence of background noise and in adverse conditions. Listening with a cochlear implant remains very demanding and most listeners report high levels of listening effort. The aim of current auditory prostheses and cochlear implants is not only restore speech understanding, but also to restore all the cognitive functions that are associated to a listening task (e.g., memory, executive functions, attention). Evaluating the listening effort is a new way to assess the efficiency of the hearing aids or cochlear implants. The listening effort indicates the amount of cognitive resources that are dedicated to a listening task; it evaluates also the cognitive resources remaining available for the other cognitive functions. The present study is a "pilot" aiming to evaluate listening effort for cochlear implant users. The listening effort is measured with pupillometry, i. e. by measuring the pupil dilatation in response to different stimuli. The size of the pupil is known to increase with the listening effort. The listening effort is evaluated in two different situation: speech perception in quiet and speech perception in noise. Speech comprehension is measured for the two listening conditions and cognitive functions are assessed by the MOCA (Montreal Cognitive Assessment). In addition, the subjects are asked to subjectively evaluate the amount of listening effort they used in each listening situation. The pupillometry measures will be compared for the two listening conditions. Moreover, the study will evaluate the relationship between objective (pupil dilatation) and subjective measures (self evaluation) of listening effort, and between speech comprehension, cognitive abilities and listening effort. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00023036 -
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts
|
||
Completed |
NCT03746613 -
Clinal Evaluation of Navigation Based Functional Ear Surgery Using Image Guided and Robotically Assisted Techniques
|
N/A | |
Recruiting |
NCT05568329 -
Appreciation for Music Processed by Hearing Aids
|
N/A | |
Withdrawn |
NCT05061758 -
A Trial of LY3056480 in Patients With SNLH
|
Phase 2 | |
Completed |
NCT01434446 -
The Effect of Sound Stimulation on Hearing Ability
|
N/A | |
Recruiting |
NCT06053190 -
Effects of Clear Speech on Listening Effort and Memory in Sentence Processing
|
N/A | |
Completed |
NCT03718975 -
Quality Control of CE-Certified Phonak Hearing Aids - 2018_28
|
N/A | |
Completed |
NCT06025097 -
Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.
|
Early Phase 1 | |
Recruiting |
NCT04102215 -
The Efficacy of a Minimally Invasive Direct Cochlear Access Via the HEARO Procedure
|
N/A | |
Recruiting |
NCT04108598 -
The SeaSHeL National Prospective Cohort Study
|
||
Active, not recruiting |
NCT04750642 -
Cochlear Implant With Dexamethasone Eluting Electrode Array
|
N/A | |
Completed |
NCT04120116 -
FX-322 in Adults With Stable Sensorineural Hearing Loss
|
Phase 2 | |
Recruiting |
NCT06223724 -
Status Telemetry for Cochlear Implantations
|
||
Completed |
NCT02005822 -
Congenital Cytomegalovirus: Efficacy of Antiviral Treatment
|
Phase 3 | |
Suspended |
NCT02616172 -
Autologous Bone Marrow Harvest and Transplant for Sensorineural Hearing Loss
|
Phase 1/Phase 2 | |
Completed |
NCT02259595 -
Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC
|
Phase 1 | |
Unknown status |
NCT01902914 -
Effectiveness of P02 Digital Hearing Aids
|
Phase 1/Phase 2 | |
Completed |
NCT00589511 -
Nucleus Freedom Cochlear Implant System Pediatric Post-approval Study
|
N/A | |
Completed |
NCT03288753 -
Comparison Between Neuro 1 and Neuro 2 Cochlear Implant Speech Processors
|
N/A | |
Completed |
NCT04462198 -
Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
|
Phase 1/Phase 2 |