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Seizures clinical trials

View clinical trials related to Seizures.

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NCT ID: NCT02229123 Completed - Neonatal Seizures Clinical Trials

Levetiracetam Treatment of Neonatal Seizures: Safety and Efficacy Phase II Study

LEVNEONAT-1
Start date: February 27, 2018
Phase: Phase 2
Study type: Interventional

LEVNEONAT is a multicentre French clinical trials with the aim to develop new treatment strategies for the treatment of neonatal seizures using Levetiracetam. The purpose of this study is to determine the correct dosing, safety and efficacy for intravenous levetiracetam as first line treatment in term newborn babies with seizures in hypoxic-ischemic encephalopathy context. This new anticonvulsivant drug is a promising treatment for seizures in newborns.

NCT ID: NCT02224690 Completed - Epilepsy Clinical Trials

A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults

GWPCARE4
Start date: April 28, 2015
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of GWP42003-P as adjunctive treatment in reducing the number of drop seizures when compared with placebo, in participants with Lennox-Gastaut Syndrome (LGS).

NCT ID: NCT02224560 Completed - Epilepsy Clinical Trials

Efficacy and Safety of GWP42003-P for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults

GWPCARE3
Start date: June 8, 2015
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to evaluate the efficacy of GWP42003-P as adjunctive treatment in reducing the number of drop seizures when compared with placebo in participants with Lennox-Gastaut syndrome (LGS).

NCT ID: NCT02216500 Recruiting - Seizures Clinical Trials

Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

Start date: September 2006
Phase: N/A
Study type: Interventional

Approximately a fourth of children with seizures do not respond adequately to available therapy. Ketogenic therapy has a long history as treatment for intractable epilepsy, but there is no agreement concerning how it works and what is the best way to administer it. This natural history study will collect data pertaining to both questions.

NCT ID: NCT02192814 Completed - Epilepsy Clinical Trials

Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures

Start date: June 2014
Phase: Phase 3
Study type: Interventional

EP0024 is a Phase 3, multicenter, open-label study to evaluate the safety and tolerability of intravenous (iv) lacosamide (LCM). Adjunctive iv LCM therapy (200 mg/day to 400 mg/day) will be administered for 5 days as replacement for oral LCM tablets in Japanese adults with partial-onset seizures.

NCT ID: NCT02177877 Completed - Epilepsy Clinical Trials

A Biosensor for Tracking Seizures: Linking a Wrist Accelerometer to an Online Epilepsy Diary

Start date: June 2014
Phase:
Study type: Observational

This study will assess whether a movement detecting wristwatch can accurately detect seizures and seizure characteristics and record them into an online epilepsy diary. The patients may manually record a description into the online epilepsy diary of the symptoms they experienced before, during or after the seizure.

NCT ID: NCT02161185 Terminated - Epilepsy Clinical Trials

A Long-term Safety and Tolerability Study of USL261 in Patients With Seizure Clusters

Start date: May 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the long-term safety and tolerability of USL261 in the treatment of seizure clusters.

NCT ID: NCT02160171 Completed - Neonatal Seizures Clinical Trials

ANSeR- The Algorithm for Neonatal Seizure Recognition Study

ANSeR
Start date: April 2013
Phase: N/A
Study type: Observational

A Multicentre Clinical Evaluation of a Decision Support Algorithm for Neonatal Seizure Detection: ANSeR

NCT ID: NCT02124564 Completed - Epilepsy Clinical Trials

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Start date: April 2014
Phase: Phase 3
Study type: Interventional

This study is to evaluate the long-term safety and tolerability of Lacosamide (LCM) 200 mg/day to LCM 600 mg/day taken in monotherapy in Japanese subjects who currently have partial-onset seizures with or without secondary generalization and who are treated with a single Anti-Epileptic Drug (AED) with marketing approval in Japan.

NCT ID: NCT02088957 Terminated - Clinical trials for Nonconvulsive Electrographic Seizures

Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures

Start date: March 2014
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to compare the efficacy of Brivaracetam and Phenytoin, both administered intravenously, in adult subjects experiencing nonconvulsive electrographic seizures.