Dexmedetomidine Versus Midazolam for Intensive Care Sedation of Children

Status Recruiting

Clinical Trial Summary

Dexmedetomidine will be tested against midazolam in a prospective, randomized, double-blind study of intensive care children, age 2-17 years.

The investigators' primary hypothesis is that time from end of medication to extubation will be shorter with dexmedetomidine sedation.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Sedation

Clinical Trial Details

NCT number	NCT01091818
Study type	Interventional
Source	Oslo University Hospital
Contact
Status	Recruiting
Phase	Phase 3
Start date	March 2010
Completion date	October 2011

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03399019` - Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia	N/A
Completed	`NCT03220880` - Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures
Recruiting	`NCT04820205` - Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children	N/A
Recruiting	`NCT04549623` - End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography	N/A
Recruiting	`NCT04822064` - Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural Sedation	N/A
Completed	`NCT01527903` - A Comparison Between Propofol-Remifentanil and Midazolam-Remifentanil Sedation in the Intensive Care Unit	Phase 4
Completed	`NCT01001533` - Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation	N/A
Completed	`NCT00747721` - Pharmacokinetics of Dexmedetomidine During Prolonged Infusion in ICU	Phase 1
Completed	`NCT00158873` - Pharmaco-Economic Study Of Ultiva In Intensive Care Unit(ICU)Subjects	Phase 4
Terminated	`NCT00205517` - Sedation and Psychopharmacology in Critical Care	N/A
Recruiting	`NCT04096768` - The Use of Ketamine and Dexmedetomidine in Intensive Care Sedation	Phase 3
Active, not recruiting	`NCT05082623` - The Effect of Music on Delirium, Pain, Need of Sedation, Anxiety and Vital Parameters	N/A
Suspended	`NCT03285165` - Cerebral Vascular Effects of Dexmedetomidine Versus Propofol Sedation in Intubated Mechanically Ventilated ICU Patients	Phase 2/Phase 3
Active, not recruiting	`NCT04788589` - Sedation and Ventilator Weaning Protocol in PICU	N/A
Completed	`NCT03425474` - Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy	Phase 3
Recruiting	`NCT06061159` - The ED95 of Single Intravenous Bolus Remimazolam Besylate in Pediatric Patients During General Anesthesia Induction	Phase 4
Completed	`NCT06449365` - Comparison of Intravenous V/S Nasal Atomizer Delivery of Midazolam for Conscious Sedation for No-scalpel Vasectomy	Phase 4
Completed	`NCT02171910` - Doxapram as an Additive to Propofol Sedation in Sedation for ERCP	Phase 4
Completed	`NCT02211118` - Sedation and Physiological Effects of Intranasal Dexmedetomidine in Severe COPD	Phase 4
Completed	`NCT01694745` - EUROpean Pain Audit In Neonates	N/A